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Pars plana vitrectomy for vitreoretinal complications in only seeing eyes after treatment for retinoblastoma
PURPOSE: To report the outcomes of two only seeing eyes of two cases with retinoblastoma in which vitrectomy was performed to treat vitreous hemorrhage or rhegmatogenous retinal detachment after treatment for retinoblastoma. OBSERVATIONS: Case 1 was an 8-month-old girl whose bilateral retinoblastoma...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859804/ https://www.ncbi.nlm.nih.gov/pubmed/35243141 http://dx.doi.org/10.1016/j.ajoc.2022.101367 |
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author | Nishida, Koichi Morimoto, Takeshi Suzuki, Shigenobu Iwahashi, Chiharu Imai, Hisanori Kuniyoshi, Kazuki Kusaka, Shunji |
author_facet | Nishida, Koichi Morimoto, Takeshi Suzuki, Shigenobu Iwahashi, Chiharu Imai, Hisanori Kuniyoshi, Kazuki Kusaka, Shunji |
author_sort | Nishida, Koichi |
collection | PubMed |
description | PURPOSE: To report the outcomes of two only seeing eyes of two cases with retinoblastoma in which vitrectomy was performed to treat vitreous hemorrhage or rhegmatogenous retinal detachment after treatment for retinoblastoma. OBSERVATIONS: Case 1 was an 8-month-old girl whose bilateral retinoblastoma (group D, OU) was treated by chemotherapy and focal ablation therapy. As the tumor size increased, enucleation was required in the right eye. At 4 years of age, about 1 year after the last treatment for retinoblastoma, lens-sparing vitrectomy was performed for dense, nonclearing vitreous hemorrhage, which had occurred 6 months previously. No recurrence of the tumor was found, and the patient's visual acuity improved to 0.9 postoperatively. Case 2 was a 4-month-old boy who was diagnosed with bilateral retinoblastoma (group D, OD; group C, OS) and underwent treatment, including systemic and local chemotherapy and proton beam therapy. Because large, regressed tumor masses were present in the posterior pole of the right eye, the left eye was the only seeing eye. At the age of 1 year 7 months, retinal detachment developed in the left eye 1 month after cryotherapy was performed for tumor recurrence. Although a scleral buckling procedure without drainage was performed, the retina was not reattached. The retina was reattached after vitrectomy with melphalan irrigation and silicone oil tamponade. However, recurrence was noted 6 months after the operation, and enucleation was required. CONCLUSION AND IMPORTANCE: Vitrectomy appears to be beneficial for the treatment of vision-threatening complications after retinoblastoma treatment. However, vitrectomy may be associated with the potential spread of tumor cells and/or tumor recurrence and therefore should be reserved as the last treatment modality for only seeing eyes. Careful postoperative follow-up is mandatory. |
format | Online Article Text |
id | pubmed-8859804 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-88598042022-03-02 Pars plana vitrectomy for vitreoretinal complications in only seeing eyes after treatment for retinoblastoma Nishida, Koichi Morimoto, Takeshi Suzuki, Shigenobu Iwahashi, Chiharu Imai, Hisanori Kuniyoshi, Kazuki Kusaka, Shunji Am J Ophthalmol Case Rep Case Report PURPOSE: To report the outcomes of two only seeing eyes of two cases with retinoblastoma in which vitrectomy was performed to treat vitreous hemorrhage or rhegmatogenous retinal detachment after treatment for retinoblastoma. OBSERVATIONS: Case 1 was an 8-month-old girl whose bilateral retinoblastoma (group D, OU) was treated by chemotherapy and focal ablation therapy. As the tumor size increased, enucleation was required in the right eye. At 4 years of age, about 1 year after the last treatment for retinoblastoma, lens-sparing vitrectomy was performed for dense, nonclearing vitreous hemorrhage, which had occurred 6 months previously. No recurrence of the tumor was found, and the patient's visual acuity improved to 0.9 postoperatively. Case 2 was a 4-month-old boy who was diagnosed with bilateral retinoblastoma (group D, OD; group C, OS) and underwent treatment, including systemic and local chemotherapy and proton beam therapy. Because large, regressed tumor masses were present in the posterior pole of the right eye, the left eye was the only seeing eye. At the age of 1 year 7 months, retinal detachment developed in the left eye 1 month after cryotherapy was performed for tumor recurrence. Although a scleral buckling procedure without drainage was performed, the retina was not reattached. The retina was reattached after vitrectomy with melphalan irrigation and silicone oil tamponade. However, recurrence was noted 6 months after the operation, and enucleation was required. CONCLUSION AND IMPORTANCE: Vitrectomy appears to be beneficial for the treatment of vision-threatening complications after retinoblastoma treatment. However, vitrectomy may be associated with the potential spread of tumor cells and/or tumor recurrence and therefore should be reserved as the last treatment modality for only seeing eyes. Careful postoperative follow-up is mandatory. Elsevier 2022-02-02 /pmc/articles/PMC8859804/ /pubmed/35243141 http://dx.doi.org/10.1016/j.ajoc.2022.101367 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Nishida, Koichi Morimoto, Takeshi Suzuki, Shigenobu Iwahashi, Chiharu Imai, Hisanori Kuniyoshi, Kazuki Kusaka, Shunji Pars plana vitrectomy for vitreoretinal complications in only seeing eyes after treatment for retinoblastoma |
title | Pars plana vitrectomy for vitreoretinal complications in only seeing eyes after treatment for retinoblastoma |
title_full | Pars plana vitrectomy for vitreoretinal complications in only seeing eyes after treatment for retinoblastoma |
title_fullStr | Pars plana vitrectomy for vitreoretinal complications in only seeing eyes after treatment for retinoblastoma |
title_full_unstemmed | Pars plana vitrectomy for vitreoretinal complications in only seeing eyes after treatment for retinoblastoma |
title_short | Pars plana vitrectomy for vitreoretinal complications in only seeing eyes after treatment for retinoblastoma |
title_sort | pars plana vitrectomy for vitreoretinal complications in only seeing eyes after treatment for retinoblastoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859804/ https://www.ncbi.nlm.nih.gov/pubmed/35243141 http://dx.doi.org/10.1016/j.ajoc.2022.101367 |
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