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The PI3K/AKT/mTOR signaling pathway is aberrantly activated in primary central nervous system lymphoma and correlated with a poor prognosis
BACKGROUND: Primary central nervous system lymphoma (PCNSL) is a specific subtype of non-Hodgkin lymphoma that is highly invasive and confined to the central nervous system (CNS). The vast majority of PCNSLs are diffuse large B-cell lymphomas (DLBCLs). PCNSL is a highly heterogeneous disease, and it...
Autores principales: | Zhang, Xiaowei, Wu, Yuchen, Sun, Xuefei, Cui, Qu, Bai, Xueyan, Dong, Gehong, Gao, Zifen, Wang, Yaming, Gao, Chunji, Sun, Shengjun, Ji, Nan, Liu, Yuanbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8859899/ https://www.ncbi.nlm.nih.gov/pubmed/35184749 http://dx.doi.org/10.1186/s12885-022-09275-z |
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