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Kinetic Modeling to Accelerate the Development of Nucleic Acid Formulations
[Image: see text] A critical hurdle in the clinical translation of nucleic acid drugs is the inefficiency in testing formulations for therapeutic potential. Specifically, the ability to quantitatively predict gene expression is lacking when transitioning between cell culture and animal studies. We a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860063/ https://www.ncbi.nlm.nih.gov/pubmed/34636541 http://dx.doi.org/10.1021/acsnano.1c04555 |