Quantitative profiling of adaptation to cyclin E overproduction

Cyclin E/CDK2 drives cell cycle progression from G1 to S phase. Despite the toxicity of cyclin E overproduction in mammalian cells, the cyclin E gene is overexpressed in some cancers. To further understand how cells can tolerate high cyclin E, we characterized non-transformed epithelial cells subjec...

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Detalles Bibliográficos
Autores principales: Limas, Juanita C, Littlejohn, Amiee N, House, Amy M, Kedziora, Katarzyna M, Mouery, Brandon L, Ma, Boyang, Fleifel, Dalia, Walens, Andrea, Aleman, Maria M, Dominguez, Daniel, Cook, Jeanette Gowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860095/
https://www.ncbi.nlm.nih.gov/pubmed/35173014
http://dx.doi.org/10.26508/lsa.202201378

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