Cargando…

Locomotor and histological changes in a cuprizone-induced animal model of multiple sclerosis: comparison between alpha-tocopherol and fingolimod

BACKGROUND AND PURPOSE: Fingolimod is a sphingosine 1-phosphate receptor modulator used to treat multiple sclerosis (MS). Alpha-tocopherol (AT) has been found to improve motor function in an animal model of MS. In the present study, the effects of AT and fingolimod on the locomotor function and hist...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mitra, Nilesh Kumar, Singh, Nermesh Singh A/L Gurdib, Wadingasafi, Nurul Ain Najihah Binti, Chellian, Jestin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860104/ https://www.ncbi.nlm.nih.gov/pubmed/35280835 http://dx.doi.org/10.4103/1735-5362.335172

Ejemplares similares

Evaluation of neuroprotective effects of alpha-tocopherol in cuprizone-induced demyelination model of multiple sclerosis
por: Mitra, Nilesh Kumar, et al.
Publicado: (2020)

Ameliorative effects of Fingolimod (FTY720) on microglial activation and psychosis-related behavior in short term cuprizone exposed mice
por: Li, Siyao, et al.
Publicado: (2023)

Development and evaluation of nanostructured lipid carrier-based hydrogel for topical delivery of 5-fluorouracil
por: Rajinikanth, Paruvathanahalli Siddalingam, et al.
Publicado: (2016)

Alpha-tocopherol and MRI Outcomes in Multiple Sclerosis – Association and Prediction
por: Løken-Amsrud, Kristin I., et al.
Publicado: (2013)

Histological and Top-Down Proteomic Analyses of the Visual Pathway in the Cuprizone Demyelination Model
por: Almuslehi, Mohammed S. M., et al.
Publicado: (2022)

Alpha-tocopherol: looking beyond an antioxidant
por: Engin, Kaya Nusret
Publicado: (2009)

Alpha-Tocopherol Transfer Protein (α-TTP): Insights from Alpha-Tocopherol Transfer Protein Knockout Mice
por: Lim, Yunsook, et al.
Publicado: (2007)

Remyelination in Multiple Sclerosis: Findings in the Cuprizone Model
por: Leo, Heinig, et al.
Publicado: (2022)

Metabolomic analysis of serum alpha-tocopherol among men in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study
por: Lawrence, Wayne R., et al.
Publicado: (2022)

Determination of Seminal Concentration of Fingolimod and Fingolimod‐Phosphate in Multiple Sclerosis Patients Receiving Chronic Treatment With Fingolimod
por: David, Olivier J., et al.
Publicado: (2017)

The Cuprizone Mouse Model: A Comparative Study of Cuprizone Formulations from Different Manufacturers
por: Beecken, Malena, et al.
Publicado: (2023)

Progressive ataxia due to alpha-tocopherol deficiency in Pakistan
por: Mansoor, Salman, et al.
Publicado: (2016)

Neurobehavioral, biochemical and histological assessment of the effects of resveratrol on cuprizone-induced demyelination in mice: role of autophagy modulation
por: Samy, Doaa M., et al.
Publicado: (2023)

Fingolimod (FTY720): First approved oral therapy for multiple sclerosis
por: Sharma, Sushil, et al.
Publicado: (2011)

Development and validation of a novel HILIC method for the quantification of low-levels of cuprizone in cuprizone-containing chow
por: Zheng, Fengmei, et al.
Publicado: (2021)

Oligodendrocyte death and myelin loss in the cuprizone model: an updated overview of the intrinsic and extrinsic causes of cuprizone demyelination
por: Zirngibl, Martin, et al.
Publicado: (2022)

Alpha-tocopherol succinate- and AMD3100-mobilized progenitors mitigate radiation combined injury in mice
por: Singh, Vijay K., et al.
Publicado: (2014)

Action of cholecalciferol and alpha-tocopherol on Staphylococcus aureus efflux pumps
por: Tintino, Saulo R., et al.
Publicado: (2016)

Strain differences in cuprizone induced demyelination
por: Yu, Qili, et al.
Publicado: (2017)

The Cuprizone Model: Dos and Do Nots
por: Zhan, Jiangshan, et al.
Publicado: (2020)

Fingolimod: The first oral drug approved by food and drug administration; A breakthrough in treatment of multiple sclerosis
por: Singh, Manish, et al.
Publicado: (2011)

Tolterodine Tartrate Proniosomal Gel Transdermal Delivery for Overactive Bladder
por: Rajabalaya, Rajan, et al.
Publicado: (2016)

Modulation of Cardiac Autonomic Function by Fingolimod Initiation and Predictors for Fingolimod Induced Bradycardia in Patients with Multiple Sclerosis
por: Li, Kai, et al.
Publicado: (2017)

Histological validation of fast macromolecular proton fraction mapping as a quantitative myelin imaging method in the cuprizone demyelination model
por: Khodanovich, Marina Yu, et al.
Publicado: (2017)

Multiple Sclerosis Relapses Following Cessation of Fingolimod
por: Malpas, Charles B., et al.
Publicado: (2022)

Alpha-tocopherol concentration in serum and colostrum of mothers with gestational diabetes mellitus
por: Resende, Fernanda Barros S., et al.
Publicado: (2014)

Nodular panniculitis in a cat with high alpha tocopherol concentration in serum
por: Steffl, Martin, et al.
Publicado: (2020)

Vitamin E (Alpha-Tocopherol) Metabolism and Nutrition in Chronic Kidney Disease
por: Galli, Francesco, et al.
Publicado: (2022)

Assessment of (18)F-PBR-111 in the Cuprizone Mouse Model of Multiple Sclerosis
por: Jewells, Valerie L., et al.
Publicado: (2021)

Cuprizone Intoxication Results in Myelin Vacuole Formation
por: Joost, Sarah, et al.
Publicado: (2022)

Cuprizone feeding induces swollen astrocyte endfeet
por: Fallier-Becker, Petra, et al.
Publicado: (2022)

Astrocytes: Lessons Learned from the Cuprizone Model
por: Kipp, Markus
Publicado: (2023)

Similarities and differences between alpha-tocopherol and gamma-tocopherol in amelioration of inflammation, oxidative stress and pre-fibrosis in hyperglycemia induced acute kidney inflammation
por: Shin, Hanna, et al.
Publicado: (2016)

Quercetin and metformin synergistically reverse endothelial dysfunction in the isolated aorta of streptozotocin-nicotinamide- induced diabetic rats
por: Chellian, Jestin, et al.
Publicado: (2022)

Influence of rutin and its combination with metformin on vascular functions in type 1 diabetes
por: David, Sheba R., et al.
Publicado: (2023)

Alpha-Tocopherol Counteracts the Cytotoxicity Induced by Ochratoxin A in Primary Porcine Fibroblasts
por: Fusi, Eleonora, et al.
Publicado: (2010)

Alpha-tocopherol transfer protein disruption confers resistance to malarial infection in mice
por: Herbas, Maria S, et al.
Publicado: (2010)

Time course and dose response of alpha tocopherol on oxidative stress in haemodialysis patients
por: Reed, Ashleigh, et al.
Publicado: (2009)

Hepatoprotective effect of curcumin and alpha-tocopherol against cisplatin-induced oxidative stress
por: Palipoch, Sarawoot, et al.
Publicado: (2014)

Self-reported adherence and biomarker levels of CoQ10 and alpha-tocopherol
por: Vitolins, Mara Z, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_4jlm7p8gbfs9kfg6itt1jhei91