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Actin R256 Mono-methylation Is a Conserved Post-translational Modification Involved in Transcription
Nuclear actin has been elusive due to the lack of knowledge about molecular mechanisms. From actin-containing chromatin remodeling complexes, we discovered an arginine mono-methylation mark on an evolutionarily conserved R256 residue of actin (R256me1). Actin R256 mutations in yeast affect nuclear f...
Autores principales: | Kumar, Ashok, Zhong, Yuan, Albrecht, Amelie, Sang, Pau Biak, Maples, Adrian, Liu, Zhenan, Vinayachandran, Vinesh, Reja, Rohit, Lee, Chia-Fang, Kumar, Ashutosh, Chen, Jiyuan, Xiao, Jing, Park, Bongsoo, Shen, Jianjun, Liu, Bin, Person, Maria D., Trybus, Kathleen M., Zhang, Kam Y.J., Pugh, B. Franklin, Kamm, Kristine E., Milewicz, Dianna M., Shen, Xuetong, Kapoor, Prabodh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860185/ https://www.ncbi.nlm.nih.gov/pubmed/32997990 http://dx.doi.org/10.1016/j.celrep.2020.108172 |
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