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Characterization of SARS-CoV-2 Omicron spike RBD reveals significantly decreased stability, severe evasion of neutralizing-antibody recognition but unaffected engagement by decoy ACE2 modified for enhanced RBD binding
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860268/ https://www.ncbi.nlm.nih.gov/pubmed/35190526 http://dx.doi.org/10.1038/s41392-022-00914-2 |
| _version_ | 1784654634163372032 |
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| author | Lin, Sheng Chen, Zimin Zhang, Xindan Wen, Ao Yuan, Xin Yu, Chongzhang Yang, Jing He, Bin Cao, Yu Lu, Guangwen |
| author_facet | Lin, Sheng Chen, Zimin Zhang, Xindan Wen, Ao Yuan, Xin Yu, Chongzhang Yang, Jing He, Bin Cao, Yu Lu, Guangwen |
| author_sort | Lin, Sheng |
| collection | PubMed |
| description | |
| format | Online Article Text |
| id | pubmed-8860268 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | Nature Publishing Group UK |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-88602682022-02-22 Characterization of SARS-CoV-2 Omicron spike RBD reveals significantly decreased stability, severe evasion of neutralizing-antibody recognition but unaffected engagement by decoy ACE2 modified for enhanced RBD binding Lin, Sheng Chen, Zimin Zhang, Xindan Wen, Ao Yuan, Xin Yu, Chongzhang Yang, Jing He, Bin Cao, Yu Lu, Guangwen Signal Transduct Target Ther Letter Nature Publishing Group UK 2022-02-21 /pmc/articles/PMC8860268/ /pubmed/35190526 http://dx.doi.org/10.1038/s41392-022-00914-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
| spellingShingle | Letter Lin, Sheng Chen, Zimin Zhang, Xindan Wen, Ao Yuan, Xin Yu, Chongzhang Yang, Jing He, Bin Cao, Yu Lu, Guangwen Characterization of SARS-CoV-2 Omicron spike RBD reveals significantly decreased stability, severe evasion of neutralizing-antibody recognition but unaffected engagement by decoy ACE2 modified for enhanced RBD binding |
| title | Characterization of SARS-CoV-2 Omicron spike RBD reveals significantly decreased stability, severe evasion of neutralizing-antibody recognition but unaffected engagement by decoy ACE2 modified for enhanced RBD binding |
| title_full | Characterization of SARS-CoV-2 Omicron spike RBD reveals significantly decreased stability, severe evasion of neutralizing-antibody recognition but unaffected engagement by decoy ACE2 modified for enhanced RBD binding |
| title_fullStr | Characterization of SARS-CoV-2 Omicron spike RBD reveals significantly decreased stability, severe evasion of neutralizing-antibody recognition but unaffected engagement by decoy ACE2 modified for enhanced RBD binding |
| title_full_unstemmed | Characterization of SARS-CoV-2 Omicron spike RBD reveals significantly decreased stability, severe evasion of neutralizing-antibody recognition but unaffected engagement by decoy ACE2 modified for enhanced RBD binding |
| title_short | Characterization of SARS-CoV-2 Omicron spike RBD reveals significantly decreased stability, severe evasion of neutralizing-antibody recognition but unaffected engagement by decoy ACE2 modified for enhanced RBD binding |
| title_sort | characterization of sars-cov-2 omicron spike rbd reveals significantly decreased stability, severe evasion of neutralizing-antibody recognition but unaffected engagement by decoy ace2 modified for enhanced rbd binding |
| topic | Letter |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860268/ https://www.ncbi.nlm.nih.gov/pubmed/35190526 http://dx.doi.org/10.1038/s41392-022-00914-2 |
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