Cargando…

Perineural spread in head-and-neck malignancies: Imaging findings – An updated literature review

Perineural spread (PNS) represents the tumor’s ability to disseminate along nerves. The aim of this article is to review the relevant literature about the PNS in head-and-neck tumors. The important information for imaging analysis is summarized in a diagnostic flowchart. The pathogenesis, clinical s...

Descripción completa

Detalles Bibliográficos
Autores principales: Medvedev, Olga, Hedesiu, Mihaela, Ciurea, Anca, Lenghel, Manuela, Rotar, Horatiu, Dinu, Cristian, Roman, Rares, Termure, Dragos, Csutak, Csaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860315/
https://www.ncbi.nlm.nih.gov/pubmed/34255618
http://dx.doi.org/10.17305/bjbms.2021.5897
_version_ 1784654645303443456
author Medvedev, Olga
Hedesiu, Mihaela
Ciurea, Anca
Lenghel, Manuela
Rotar, Horatiu
Dinu, Cristian
Roman, Rares
Termure, Dragos
Csutak, Csaba
author_facet Medvedev, Olga
Hedesiu, Mihaela
Ciurea, Anca
Lenghel, Manuela
Rotar, Horatiu
Dinu, Cristian
Roman, Rares
Termure, Dragos
Csutak, Csaba
author_sort Medvedev, Olga
collection PubMed
description Perineural spread (PNS) represents the tumor’s ability to disseminate along nerves. The aim of this article is to review the relevant literature about the PNS in head-and-neck tumors. The important information for imaging analysis is summarized in a diagnostic flowchart. The pathogenesis, clinical signs, prognostic importance, and technical considerations for computer tomography and magnetic resonance imaging are briefly discussed. The anatomical pathways of the cranial nerves (CNs) and the main checkpoints are synthesized. Most commonly affected nerves are the trigeminal and facial, although any of the CNs may be involved. The described imaging features represent important clues for an optimal differential diagnosis. PNS worsens the prognosis and significantly changes the treatment, thus radiologists should be aware of this entity and be able to find it on imaging in the appropriate clinical context.
format Online
Article
Text
id pubmed-8860315
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
record_format MEDLINE/PubMed
spelling pubmed-88603152022-02-27 Perineural spread in head-and-neck malignancies: Imaging findings – An updated literature review Medvedev, Olga Hedesiu, Mihaela Ciurea, Anca Lenghel, Manuela Rotar, Horatiu Dinu, Cristian Roman, Rares Termure, Dragos Csutak, Csaba Bosn J Basic Med Sci Review Article Perineural spread (PNS) represents the tumor’s ability to disseminate along nerves. The aim of this article is to review the relevant literature about the PNS in head-and-neck tumors. The important information for imaging analysis is summarized in a diagnostic flowchart. The pathogenesis, clinical signs, prognostic importance, and technical considerations for computer tomography and magnetic resonance imaging are briefly discussed. The anatomical pathways of the cranial nerves (CNs) and the main checkpoints are synthesized. Most commonly affected nerves are the trigeminal and facial, although any of the CNs may be involved. The described imaging features represent important clues for an optimal differential diagnosis. PNS worsens the prognosis and significantly changes the treatment, thus radiologists should be aware of this entity and be able to find it on imaging in the appropriate clinical context. Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2022-02 2021-06-29 /pmc/articles/PMC8860315/ /pubmed/34255618 http://dx.doi.org/10.17305/bjbms.2021.5897 Text en Copyright: © The Author(s) (2022) https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License
spellingShingle Review Article
Medvedev, Olga
Hedesiu, Mihaela
Ciurea, Anca
Lenghel, Manuela
Rotar, Horatiu
Dinu, Cristian
Roman, Rares
Termure, Dragos
Csutak, Csaba
Perineural spread in head-and-neck malignancies: Imaging findings – An updated literature review
title Perineural spread in head-and-neck malignancies: Imaging findings – An updated literature review
title_full Perineural spread in head-and-neck malignancies: Imaging findings – An updated literature review
title_fullStr Perineural spread in head-and-neck malignancies: Imaging findings – An updated literature review
title_full_unstemmed Perineural spread in head-and-neck malignancies: Imaging findings – An updated literature review
title_short Perineural spread in head-and-neck malignancies: Imaging findings – An updated literature review
title_sort perineural spread in head-and-neck malignancies: imaging findings – an updated literature review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860315/
https://www.ncbi.nlm.nih.gov/pubmed/34255618
http://dx.doi.org/10.17305/bjbms.2021.5897
work_keys_str_mv AT medvedevolga perineuralspreadinheadandneckmalignanciesimagingfindingsanupdatedliteraturereview
AT hedesiumihaela perineuralspreadinheadandneckmalignanciesimagingfindingsanupdatedliteraturereview
AT ciureaanca perineuralspreadinheadandneckmalignanciesimagingfindingsanupdatedliteraturereview
AT lenghelmanuela perineuralspreadinheadandneckmalignanciesimagingfindingsanupdatedliteraturereview
AT rotarhoratiu perineuralspreadinheadandneckmalignanciesimagingfindingsanupdatedliteraturereview
AT dinucristian perineuralspreadinheadandneckmalignanciesimagingfindingsanupdatedliteraturereview
AT romanrares perineuralspreadinheadandneckmalignanciesimagingfindingsanupdatedliteraturereview
AT termuredragos perineuralspreadinheadandneckmalignanciesimagingfindingsanupdatedliteraturereview
AT csutakcsaba perineuralspreadinheadandneckmalignanciesimagingfindingsanupdatedliteraturereview