MEFV and NLRP3 Inflammasome Expression Is Attributed to Immature Macrophages and Correlates with Serum Inflammatory Proteins in Crohn´s Disease Patients

Inflammasomes are intracellular protein complexes whose activation results in proinflammatory cytokines. Inflammasomes are implicated in Crohn´s disease (CD) pathogenesis, yet the contribution of inflammasomes in intestinal epithelial cells (IECs) versus lamina propria (LP) macrophages is poorly und...

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Detalles Bibliográficos
Autores principales: Gorreja, Frida, Caër, Charles, Rush, Stephen T. A., Forsskål, Sophia K., Härtlova, Anetta, Magnusson, Maria K., Bexe Lindskog, Elinor, Börjesson, Lars G., Block, Mattias, Wick, Mary Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860375/
https://www.ncbi.nlm.nih.gov/pubmed/35190924
http://dx.doi.org/10.1007/s10753-022-01647-8

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