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SETDB1/NSD-dependent H3K9me3/H3K36me3 dual heterochromatin maintains gene expression profiles by bookmarking poised enhancers

Gene silencing by heterochromatin plays a crucial role in cell identity. Here, we characterize the localization, the biogenesis, and the function of an atypical heterochromatin, which is simultaneously enriched in the typical H3K9me3 mark and in H3K36me3, a histone mark usually associated with gene...

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Detalles Bibliográficos
Autores principales: Barral, Amandine, Pozo, Gabrielle, Ducrot, Lucas, Papadopoulos, Giorgio L., Sauzet, Sandrine, Oldfield, Andrew J., Cavalli, Giacomo, Déjardin, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860380/
https://www.ncbi.nlm.nih.gov/pubmed/35081363
http://dx.doi.org/10.1016/j.molcel.2021.12.037

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