Cargando…

Paeoniflorin mitigates PBC-induced liver fibrosis by repressing NLRP3 formation

PURPOSE: To delve into the influence of paeoniflorin (PA) on abating primary biliary cholangitis (PBC)-induced liver fibrosis and its causative role. METHODS: Our team allocated the mice to control group, PA group, PBC group and PBC+PA group. We recorded the weight change of mice in each group. We u...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yizhe, Zhang, Shujie, Luo, Xin, Zhao, Han, Xiang, Xiaoxing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860402/ https://www.ncbi.nlm.nih.gov/pubmed/35195182 http://dx.doi.org/10.1590/ACB361106

Ejemplares similares

Emerging therapies for PBC
por: Chascsa, David Maxwell Hunter, et al.
Publicado: (2020)

Measurement properties of the PBC-40 and PBC-27: a Dutch validation study
por: de Veer, Rozanne C, et al.
Publicado: (2021)

Pretransplant Evaluation and Liver Transplantation Outcome in PBC Patients
por: Mijic, Maja, et al.
Publicado: (2022)

Paeoniflorin regulates macrophage activation in dimethylnitrosamine-induced liver fibrosis in rats
por: Chen, Xiaorong, et al.
Publicado: (2012)

PBC technology subgroup report
por: Siemko, Andrzej, et al.
Publicado: (2018)

Hox-PBC Partnership Demystified
por: Sedwick, Caitlin
Publicado: (2012)

The future risk of primary biliary cholangitis (PBC) is low among patients with incidental anti‐mitochondrial antibodies but without baseline PBC
por: Duan, Weijia, et al.
Publicado: (2022)

Usefulness of the Pinch-Burn-Cut (PBC) technique for recipient hepatectomy in liver transplantation
por: Park, Yong Keun, et al.
Publicado: (2012)

Changing Nomenclature for PBC: From ‘Cirrhosis' to ‘Cholangitis'
por: Beuers, Ulrich, et al.
Publicado: (2015)

Noninvasive diagnosis of AIH/PBC overlap syndrome based on prediction models
por: Wang, Kailing, et al.
Publicado: (2022)

PD-1 inhibition plus platinum-based chemotherapy (PBC) or PBC alone in the first-line treatment of locally advanced or metastatic pulmonary lymphoepithelioma-like carcinoma
por: Zhang, Xuanye, et al.
Publicado: (2022)

Antimicrobial s-PBC Coatings for Innovative Multifunctional Water Filters
por: Sciuto, Emanuele Luigi, et al.
Publicado: (2020)

The PBC Model: Supporting Positive Behaviours in Smart Environments
por: Adewoyin, Oluwande, et al.
Publicado: (2022)

Identification of pBC218/pBC210 Genes of Bacillus cereus G9241 in Five Florida Soils Using qPCR
por: Luna, Vicki Ann, et al.
Publicado: (2014)

Paeoniflorin improves functional recovery through repressing neuroinflammation and facilitating neurogenesis in rat stroke model
por: Tang, Hongli, et al.
Publicado: (2021)

Rapid determination of paeoniflorin
por: Wiwanitkit, Viroj
Publicado: (2010)

Paeoniflorin mitigates high glucose-induced lifespan reduction by inhibiting insulin signaling in Caenorhabditis elegans
por: Liu, Tianwen, et al.
Publicado: (2023)

Gut Microbiota-Based Pharmacokinetics and the Antidepressant Mechanism of Paeoniflorin
por: Yu, Jin-Bo, et al.
Publicado: (2019)

PBC: Animal Models of Cholangiopathies and Possible Endogenous Viral Infections
por: Ninomiya, Masashi, et al.
Publicado: (2012)

Serum Ghrelin Concentration in Patients With Primary Biliary Cirrhosis (PBC)
por: Naguib, Rania, et al.
Publicado: (2021)

A change of paradigm in PBC: Pursuing normal alkaline phosphatase
por: Lleo, Ana
Publicado: (2022)

The ROS/GRK2/HIF-1α/NLRP3 Pathway Mediates Pyroptosis of Fibroblast-Like Synoviocytes and the Regulation of Monomer Derivatives of Paeoniflorin
por: Hong, Zhongyang, et al.
Publicado: (2022)

Paeoniflorin, a Natural Product With Multiple Targets in Liver Diseases—A Mini Review
por: Ma, Xiao, et al.
Publicado: (2020)

The Regulatory Effects of Paeoniflorin and Its Derivative Paeoniflorin-6′-O-Benzene Sulfonate CP-25 on Inflammation and Immune Diseases
por: Tu, Jiajie, et al.
Publicado: (2019)

Paeoniflorin prevents postoperative peritoneal adhesion formation in an experimental rat model
por: Gao, Qi, et al.
Publicado: (2017)

Paeoniflorin alleviates liver injury in hypercholesterolemic rats through the ROCK/AMPK pathway
por: Liu, Tong, et al.
Publicado: (2022)

PBC, an easy and efficient strategy for high-throughput protein C-terminome profiling
por: Zhai, Linhui, et al.
Publicado: (2022)

CXCL12-CXCR4-Mediated Chemotaxis Supports Accumulation of Mucosal-Associated Invariant T Cells Into the Liver of Patients With PBC
por: Chen, Zhilei, et al.
Publicado: (2021)

Paeoniflorin Ameliorates Colonic Fibrosis in Rats with Postinfectious Irritable Bowel Syndrome by Inhibiting the Leptin/LepRb Pathway
por: Tian, Ya-Qing, et al.
Publicado: (2022)

CTLA-4 Expression Plays a Role in PSC and PBC Progression
por: Meister, Phil, et al.
Publicado: (2020)

The Impact of Paeoniflorin on α-Synuclein Degradation Pathway
por: Cai, Zenglin, et al.
Publicado: (2015)

Paeoniflorin reduce luxS/AI-2 system-controlled biofilm formation and virulence in Streptococcus suis
por: Li, Jinpeng, et al.
Publicado: (2021)

Quantification of Paeoniflorin by Fully Validated LC–MS/MS Method: Its Application to Pharmacokinetic Interaction between Paeoniflorin and Verapamil
por: Bao, Bin, et al.
Publicado: (2022)

Intranasal delivery of paeoniflorin nanocrystals for brain targeting
por: Wu, Chaoyin, et al.
Publicado: (2020)

Paeoniflorin in Paeoniaceae: Distribution, influencing factors, and biosynthesis
por: Zhang, Xiao-Xiao, et al.
Publicado: (2022)

Promoter hypermethylation of the AE2/SLC4A2 gene in PBC
por: Arenas, Fabián, et al.
Publicado: (2019)

Comprehensive assessment of ECM turnover using serum biomarkers establishes PBC as a high-turnover autoimmune liver disease
por: Vesterhus, Mette, et al.
Publicado: (2020)

The Role of Autophagy and NLRP3 Inflammasome in Liver Fibrosis
por: Tao, Ye, et al.
Publicado: (2020)

Paeoniflorin Protects against Acetaminophen-Induced Liver Injury in Mice via JNK Signaling Pathway
por: Deng, Xinyu, et al.
Publicado: (2022)

An In Vitro Verification of the Effects of Paeoniflorin on Lipopolysaccharide-Exposed Microglia
por: Chen, Qiliang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_u9d1scq07ia7eellahvn3jkh3h