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How collagen becomes ‘stiff’
Oxidative stress following a lung injury can alter the structure of collagen, causing it to stiffen and trigger the formation of a fibrotic scar that further hardens the tissue.
Autor principal: | |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860450/ https://www.ncbi.nlm.nih.gov/pubmed/35188461 http://dx.doi.org/10.7554/eLife.77041 |
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author | Wells, Rebecca G |
author_facet | Wells, Rebecca G |
author_sort | Wells, Rebecca G |
collection | PubMed |
description | Oxidative stress following a lung injury can alter the structure of collagen, causing it to stiffen and trigger the formation of a fibrotic scar that further hardens the tissue. |
format | Online Article Text |
id | pubmed-8860450 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | eLife Sciences Publications, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-88604502022-02-23 How collagen becomes ‘stiff’ Wells, Rebecca G eLife Cell Biology Oxidative stress following a lung injury can alter the structure of collagen, causing it to stiffen and trigger the formation of a fibrotic scar that further hardens the tissue. eLife Sciences Publications, Ltd 2022-02-21 /pmc/articles/PMC8860450/ /pubmed/35188461 http://dx.doi.org/10.7554/eLife.77041 Text en © 2022, Wells https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Cell Biology Wells, Rebecca G How collagen becomes ‘stiff’ |
title | How collagen becomes ‘stiff’ |
title_full | How collagen becomes ‘stiff’ |
title_fullStr | How collagen becomes ‘stiff’ |
title_full_unstemmed | How collagen becomes ‘stiff’ |
title_short | How collagen becomes ‘stiff’ |
title_sort | how collagen becomes ‘stiff’ |
topic | Cell Biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860450/ https://www.ncbi.nlm.nih.gov/pubmed/35188461 http://dx.doi.org/10.7554/eLife.77041 |
work_keys_str_mv | AT wellsrebeccag howcollagenbecomesstiff |