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How collagen becomes ‘stiff’

Oxidative stress following a lung injury can alter the structure of collagen, causing it to stiffen and trigger the formation of a fibrotic scar that further hardens the tissue.

Detalles Bibliográficos
Autor principal: Wells, Rebecca G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860450/
https://www.ncbi.nlm.nih.gov/pubmed/35188461
http://dx.doi.org/10.7554/eLife.77041
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author Wells, Rebecca G
author_facet Wells, Rebecca G
author_sort Wells, Rebecca G
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description Oxidative stress following a lung injury can alter the structure of collagen, causing it to stiffen and trigger the formation of a fibrotic scar that further hardens the tissue.
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spelling pubmed-88604502022-02-23 How collagen becomes ‘stiff’ Wells, Rebecca G eLife Cell Biology Oxidative stress following a lung injury can alter the structure of collagen, causing it to stiffen and trigger the formation of a fibrotic scar that further hardens the tissue. eLife Sciences Publications, Ltd 2022-02-21 /pmc/articles/PMC8860450/ /pubmed/35188461 http://dx.doi.org/10.7554/eLife.77041 Text en © 2022, Wells https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Cell Biology
Wells, Rebecca G
How collagen becomes ‘stiff’
title How collagen becomes ‘stiff’
title_full How collagen becomes ‘stiff’
title_fullStr How collagen becomes ‘stiff’
title_full_unstemmed How collagen becomes ‘stiff’
title_short How collagen becomes ‘stiff’
title_sort how collagen becomes ‘stiff’
topic Cell Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860450/
https://www.ncbi.nlm.nih.gov/pubmed/35188461
http://dx.doi.org/10.7554/eLife.77041
work_keys_str_mv AT wellsrebeccag howcollagenbecomesstiff