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Sugarcane Bagasse as the Source of Nanocrystalline Cellulose for Gelatin-Free Capsule Shell

Gelatin-free capsules are possibly produced through an innovation which involves utilizing environmentally friendly materials derived from plants such as bagasse which are produced into nanocrystalline cellulose (NCC). This research was conducted to report the extraction and characterization of NCC...

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Autores principales: Sabara, Zakir, Mutmainnah, Alfirah, Kalsum, Ummu, Afiah, Irma Nur, Husna, Ismalia, Saregar, Antomi, Irzaman, Umam, Rofiqul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860549/
https://www.ncbi.nlm.nih.gov/pubmed/35198027
http://dx.doi.org/10.1155/2022/9889127
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author Sabara, Zakir
Mutmainnah, Alfirah
Kalsum, Ummu
Afiah, Irma Nur
Husna, Ismalia
Saregar, Antomi
Irzaman,
Umam, Rofiqul
author_facet Sabara, Zakir
Mutmainnah, Alfirah
Kalsum, Ummu
Afiah, Irma Nur
Husna, Ismalia
Saregar, Antomi
Irzaman,
Umam, Rofiqul
author_sort Sabara, Zakir
collection PubMed
description Gelatin-free capsules are possibly produced through an innovation which involves utilizing environmentally friendly materials derived from plants such as bagasse which are produced into nanocrystalline cellulose (NCC). This research was conducted to report the extraction and characterization of NCC from the abundant industrial plantation waste of sugarcane and its application as the base material for gelatin-free capsule shell material. The process involved using different concentrations of NCC at 1%, 2%, 4%, and 7% (in wt. %) with the addition of 1% hydroxypropyl methylcellulose (HPMC) (in wt. %) and 1% carbopol (in wt. %). Moreover, the NCC capsules obtained from sugarcane bagasse were tested for moisture content, tensile strength, elongation, solubility, and pH. The results showed that sugarcane bagasse contains 40–50% cellulose, 6.15%–9.5% moisture content which indicates they are potentially better in terms of storage, 7.25–7.85 pH, and 0.05–0.136 MPa gel strength, and the elongation value ranges from 7.19 to 87.51%. These values were discovered to have satisfied the standard requirements as indicated by the optimal concentration of 4% NCC +1% HPMC, which is in line with the Japanese Industrial Standard (JIS), thereby leading to the consideration of the material safe to be used as raw material in making capsule shells.
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spelling pubmed-88605492022-02-22 Sugarcane Bagasse as the Source of Nanocrystalline Cellulose for Gelatin-Free Capsule Shell Sabara, Zakir Mutmainnah, Alfirah Kalsum, Ummu Afiah, Irma Nur Husna, Ismalia Saregar, Antomi Irzaman, Umam, Rofiqul Int J Biomater Research Article Gelatin-free capsules are possibly produced through an innovation which involves utilizing environmentally friendly materials derived from plants such as bagasse which are produced into nanocrystalline cellulose (NCC). This research was conducted to report the extraction and characterization of NCC from the abundant industrial plantation waste of sugarcane and its application as the base material for gelatin-free capsule shell material. The process involved using different concentrations of NCC at 1%, 2%, 4%, and 7% (in wt. %) with the addition of 1% hydroxypropyl methylcellulose (HPMC) (in wt. %) and 1% carbopol (in wt. %). Moreover, the NCC capsules obtained from sugarcane bagasse were tested for moisture content, tensile strength, elongation, solubility, and pH. The results showed that sugarcane bagasse contains 40–50% cellulose, 6.15%–9.5% moisture content which indicates they are potentially better in terms of storage, 7.25–7.85 pH, and 0.05–0.136 MPa gel strength, and the elongation value ranges from 7.19 to 87.51%. These values were discovered to have satisfied the standard requirements as indicated by the optimal concentration of 4% NCC +1% HPMC, which is in line with the Japanese Industrial Standard (JIS), thereby leading to the consideration of the material safe to be used as raw material in making capsule shells. Hindawi 2022-02-14 /pmc/articles/PMC8860549/ /pubmed/35198027 http://dx.doi.org/10.1155/2022/9889127 Text en Copyright © 2022 Zakir Sabara et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Sabara, Zakir
Mutmainnah, Alfirah
Kalsum, Ummu
Afiah, Irma Nur
Husna, Ismalia
Saregar, Antomi
Irzaman,
Umam, Rofiqul
Sugarcane Bagasse as the Source of Nanocrystalline Cellulose for Gelatin-Free Capsule Shell
title Sugarcane Bagasse as the Source of Nanocrystalline Cellulose for Gelatin-Free Capsule Shell
title_full Sugarcane Bagasse as the Source of Nanocrystalline Cellulose for Gelatin-Free Capsule Shell
title_fullStr Sugarcane Bagasse as the Source of Nanocrystalline Cellulose for Gelatin-Free Capsule Shell
title_full_unstemmed Sugarcane Bagasse as the Source of Nanocrystalline Cellulose for Gelatin-Free Capsule Shell
title_short Sugarcane Bagasse as the Source of Nanocrystalline Cellulose for Gelatin-Free Capsule Shell
title_sort sugarcane bagasse as the source of nanocrystalline cellulose for gelatin-free capsule shell
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860549/
https://www.ncbi.nlm.nih.gov/pubmed/35198027
http://dx.doi.org/10.1155/2022/9889127
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