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Unique properties of spacer acquisition by the type III-A CRISPR-Cas system
Type III CRISPR-Cas systems have a unique mode of interference, involving crRNA-guided recognition of nascent RNA and leading to DNA and RNA degradation. How type III systems acquire new CRISPR spacers is currently not well understood. Here, we characterize CRISPR spacer uptake by a type III-A syste...
Autores principales: | Zhang, Xinfu, Garrett, Sandra, Graveley, Brenton R, Terns, Michael P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860593/ https://www.ncbi.nlm.nih.gov/pubmed/34893878 http://dx.doi.org/10.1093/nar/gkab1193 |
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