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Unique properties of spacer acquisition by the type III-A CRISPR-Cas system

Type III CRISPR-Cas systems have a unique mode of interference, involving crRNA-guided recognition of nascent RNA and leading to DNA and RNA degradation. How type III systems acquire new CRISPR spacers is currently not well understood. Here, we characterize CRISPR spacer uptake by a type III-A syste...

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Detalles Bibliográficos
Autores principales: Zhang, Xinfu, Garrett, Sandra, Graveley, Brenton R, Terns, Michael P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860593/
https://www.ncbi.nlm.nih.gov/pubmed/34893878
http://dx.doi.org/10.1093/nar/gkab1193

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