Cargando…

53BP1-ACLY-SLBP-coordinated activation of replication-dependent histone biogenesis maintains genomic integrity

p53-binding protein 1 (53BP1) regulates the DNA double-strand break (DSB) repair pathway and maintains genomic integrity. Here we found that 53BP1 functions as a molecular scaffold for the nucleoside diphosphate kinase-mediated phosphorylation of ATP-citrate lyase (ACLY) which enhances the ACLY acti...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, TingTing, Jun, Semo, Choi, Eun-Ji, Sun, Jiao, Yang, Eun-Bi, Lee, Hyun-Seo, Kim, Sang-Yong, Fahmi, Naima Ahmed, Jiang, Qibing, Zhang, Wei, Yong, Jeongsik, Lee, Jung-Hee, You, Ho Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860602/
https://www.ncbi.nlm.nih.gov/pubmed/35037047
http://dx.doi.org/10.1093/nar/gkab1300

Ejemplares similares