Cargando…

53BP1-ACLY-SLBP-coordinated activation of replication-dependent histone biogenesis maintains genomic integrity

p53-binding protein 1 (53BP1) regulates the DNA double-strand break (DSB) repair pathway and maintains genomic integrity. Here we found that 53BP1 functions as a molecular scaffold for the nucleoside diphosphate kinase-mediated phosphorylation of ATP-citrate lyase (ACLY) which enhances the ACLY acti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, TingTing, Jun, Semo, Choi, Eun-Ji, Sun, Jiao, Yang, Eun-Bi, Lee, Hyun-Seo, Kim, Sang-Yong, Fahmi, Naima Ahmed, Jiang, Qibing, Zhang, Wei, Yong, Jeongsik, Lee, Jung-Hee, You, Ho Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860602/ https://www.ncbi.nlm.nih.gov/pubmed/35037047 http://dx.doi.org/10.1093/nar/gkab1300

Ejemplares similares

Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin
por: Casas-Delucchi, Corella S., et al.
Publicado: (2012)

Histone H2B mono-ubiquitylation maintains genomic integrity at stalled replication forks
por: Northam, Matthew R., et al.
Publicado: (2016)

Opposing roles for 53BP1 during homologous recombination
por: Kakarougkas, Andreas, et al.
Publicado: (2013)

USP11 acts as a histone deubiquitinase functioning in chromatin reorganization during DNA repair
por: Ting, Xia, et al.
Publicado: (2019)

ZMYM2 restricts 53BP1 at DNA double-strand breaks to favor BRCA1 loading and homologous recombination
por: Lee, Doohyung, et al.
Publicado: (2022)

METTL3-mediated m(6)A modification stabilizes TERRA and maintains telomere stability
por: Chen, Liping, et al.
Publicado: (2022)

Cooperative activation of the ATR checkpoint kinase by TopBP1 and damaged DNA
por: Choi, Jun-Hyuk, et al.
Publicado: (2009)

Acetylation of 53BP1 dictates the DNA double strand break repair pathway
por: Guo, Xiang, et al.
Publicado: (2018)

HSF2BP negatively regulates homologous recombination in DNA interstrand crosslink repair
por: Sato, Koichi, et al.
Publicado: (2020)

53BP1 promotes microhomology-mediated end-joining in G1-phase cells
por: Xiong, Xiahui, et al.
Publicado: (2015)

HDGFRP3 interaction with 53BP1 promotes DNA double-strand break repair
por: Zhang, Zhen, et al.
Publicado: (2023)

Ectopic expression of RNF168 and 53BP1 increases mutagenic but not physiological non-homologous end joining
por: Zong, Dali, et al.
Publicado: (2015)

Histone variant Htz1 promotes histone H3 acetylation to enhance nucleotide excision repair in Htz1 nucleosomes
por: Yu, Yachuan, et al.
Publicado: (2013)

DNA catenation maintains structure of human metaphase chromosomes
por: Bauer, David L. V., et al.
Publicado: (2012)

Co-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resection
por: Kakarougkas, Andreas, et al.
Publicado: (2013)

High levels of TopBP1 induce ATR-dependent shut-down of rRNA transcription and nucleolar segregation
por: Sokka, Miiko, et al.
Publicado: (2015)

CK2 kinase-mediated PHF8 phosphorylation controls TopBP1 stability to regulate DNA replication
por: Feng, Haihua, et al.
Publicado: (2020)

DNA damage triggers SAF-A and RNA biogenesis factors exclusion from chromatin coupled to R-loops removal
por: Britton, Sébastien, et al.
Publicado: (2014)

Strong suppression of gene conversion with increasing DNA double-strand break load delimited by 53BP1 and RAD52
por: Mladenov, Emil, et al.
Publicado: (2020)

The amino-terminal tails of histones H2A and H3 coordinate efficient base excision repair, DNA damage signaling and postreplication repair in Saccharomyces cerevisiae
por: Meas, Rithy, et al.
Publicado: (2015)

Chromosome thripsis by DNA double strand break clusters causes enhanced cell lethality, chromosomal translocations and 53BP1-recruitment
por: Schipler, Agnes, et al.
Publicado: (2016)

Oncogenic KRAS drives radioresistance through upregulation of NRF2-53BP1-mediated non-homologous end-joining repair
por: Yang, Linlin, et al.
Publicado: (2021)

Alternative lengthening of telomeres can be maintained by preferential elongation of lagging strands
por: Min, Jaewon, et al.
Publicado: (2017)

The chromatin remodeler RSF1 coordinates epigenetic marks for transcriptional repression and DSB repair
por: Min, Sunwoo, et al.
Publicado: (2021)

RAD18 promotes DNA double-strand break repair during G1 phase through chromatin retention of 53BP1
por: Watanabe, Kenji, et al.
Publicado: (2009)

Oxidative stress during mitochondrial biogenesis compromises mtDNA integrity in growing hearts and induces a global DNA repair response
por: Pohjoismäki, Jaakko L. O., et al.
Publicado: (2012)

FANCJ is essential to maintain microsatellite structure genome-wide during replication stress
por: Barthelemy, Joanna, et al.
Publicado: (2016)

Modulation of LSD1 phosphorylation by CK2/WIP1 regulates RNF168-dependent 53BP1 recruitment in response to DNA damage
por: Peng, Bin, et al.
Publicado: (2015)

SETDB1, HP1 and SUV39 promote repositioning of 53BP1 to extend resection during homologous recombination in G2 cells
por: Alagoz, Meryem, et al.
Publicado: (2015)

The histone variant H2A.Bbd is enriched at sites of DNA synthesis
por: Sansoni, Viola, et al.
Publicado: (2014)

Functional characterization and architecture of recombinant yeast SWR1 histone exchange complex
por: Lin, Chia-Liang, et al.
Publicado: (2017)

Tumour suppressor ING1b maintains genomic stability upon replication stress
por: Wong, Ronald P. C., et al.
Publicado: (2011)

PARP2 controls double-strand break repair pathway choice by limiting 53BP1 accumulation at DNA damage sites and promoting end-resection
por: Fouquin, Alexis, et al.
Publicado: (2017)

ATM–ESCO2–SMC3 axis promotes 53BP1 recruitment in response to DNA damage and safeguards genome integrity by stabilizing cohesin complex
por: Fu, Jianfeng, et al.
Publicado: (2023)

DICER-dependent biogenesis of let-7 miRNAs affects human cell response to DNA damage via targeting p21/p27
por: Liu, Bailong, et al.
Publicado: (2015)

MutSβ and histone deacetylase complexes promote expansions of trinucleotide repeats in human cells
por: Gannon, Anne-Marie M., et al.
Publicado: (2012)

Poly(ADP-ribosyl)ation mediates early phase histone eviction at DNA lesions
por: Yang, Guang, et al.
Publicado: (2020)

Drosophila bloom helicase maintains genome integrity by inhibiting recombination between divergent DNA sequences
por: Kappeler, Michael, et al.
Publicado: (2008)

DNA-PKcs is required to maintain stability of Chk1 and Claspin for optimal replication stress response
por: Lin, Yu-Fen, et al.
Publicado: (2014)

Fission yeast Stn1 maintains stability of repetitive DNA at subtelomere and ribosomal DNA regions
por: Yamamoto, Io, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_dvc6bmqcat3urapkn9dfimrdta