Performance of Non-nasopharyngeal Sample Types for Molecular Detection of SARS-CoV-2

Nasopharyngeal swabs have historically been considered the preferred specimen type for the detection of respiratory viruses, including SARS-CoV-2. However, in response to a global pandemic with shortages of swabs and specimen transport media, limited access to qualified health care personnel, and ne...

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Autores principales: Kukull, Benjamin, Shakir, Salika M., Hanson, Kimberly E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860668/
https://www.ncbi.nlm.nih.gov/pubmed/35636825
http://dx.doi.org/10.1016/j.cll.2022.02.002
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author Kukull, Benjamin
Shakir, Salika M.
Hanson, Kimberly E.
author_facet Kukull, Benjamin
Shakir, Salika M.
Hanson, Kimberly E.
author_sort Kukull, Benjamin
collection PubMed
description Nasopharyngeal swabs have historically been considered the preferred specimen type for the detection of respiratory viruses, including SARS-CoV-2. However, in response to a global pandemic with shortages of swabs and specimen transport media, limited access to qualified health care personnel, and needs for large-scale testing in nonmedical settings, alternative sample types have been validated for COVID-19 diagnosis. The purpose of this review is to highlight the diagnostic accuracy and clinical utility of non-nasopharyngeal respiratory samples for SARS-CoV-2 molecular diagnostic testing.
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spelling pubmed-88606682022-02-22 Performance of Non-nasopharyngeal Sample Types for Molecular Detection of SARS-CoV-2 Kukull, Benjamin Shakir, Salika M. Hanson, Kimberly E. Clin Lab Med Article Nasopharyngeal swabs have historically been considered the preferred specimen type for the detection of respiratory viruses, including SARS-CoV-2. However, in response to a global pandemic with shortages of swabs and specimen transport media, limited access to qualified health care personnel, and needs for large-scale testing in nonmedical settings, alternative sample types have been validated for COVID-19 diagnosis. The purpose of this review is to highlight the diagnostic accuracy and clinical utility of non-nasopharyngeal respiratory samples for SARS-CoV-2 molecular diagnostic testing. Elsevier Inc. 2022-06 2022-02-22 /pmc/articles/PMC8860668/ /pubmed/35636825 http://dx.doi.org/10.1016/j.cll.2022.02.002 Text en © 2022 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Kukull, Benjamin
Shakir, Salika M.
Hanson, Kimberly E.
Performance of Non-nasopharyngeal Sample Types for Molecular Detection of SARS-CoV-2
title Performance of Non-nasopharyngeal Sample Types for Molecular Detection of SARS-CoV-2
title_full Performance of Non-nasopharyngeal Sample Types for Molecular Detection of SARS-CoV-2
title_fullStr Performance of Non-nasopharyngeal Sample Types for Molecular Detection of SARS-CoV-2
title_full_unstemmed Performance of Non-nasopharyngeal Sample Types for Molecular Detection of SARS-CoV-2
title_short Performance of Non-nasopharyngeal Sample Types for Molecular Detection of SARS-CoV-2
title_sort performance of non-nasopharyngeal sample types for molecular detection of sars-cov-2
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860668/
https://www.ncbi.nlm.nih.gov/pubmed/35636825
http://dx.doi.org/10.1016/j.cll.2022.02.002
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