Case Reports of Acute Transverse Myelitis Associated With mRNA Vaccine for COVID-19

Acute transverse myelitis (ATM) has been reported as rare complication of vaccination. Herein, we report 2 cases of ATM after the administration of an mRNA vaccine for coronavirus disease 2019 (COVID-19). The first one is an 81-year-old man who received the BNT162b2 vaccine. He presented with bilate...

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Autores principales: Eom, Hyunjong, Kim, Seung Woo, Kim, Minkyoung, Kim, Ye Eun, Kim, Ji Hyun, Shin, Ha Young, Lee, Hye Lim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860770/
https://www.ncbi.nlm.nih.gov/pubmed/35191229
http://dx.doi.org/10.3346/jkms.2022.37.e52
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author Eom, Hyunjong
Kim, Seung Woo
Kim, Minkyoung
Kim, Ye Eun
Kim, Ji Hyun
Shin, Ha Young
Lee, Hye Lim
author_facet Eom, Hyunjong
Kim, Seung Woo
Kim, Minkyoung
Kim, Ye Eun
Kim, Ji Hyun
Shin, Ha Young
Lee, Hye Lim
author_sort Eom, Hyunjong
collection PubMed
description Acute transverse myelitis (ATM) has been reported as rare complication of vaccination. Herein, we report 2 cases of ATM after the administration of an mRNA vaccine for coronavirus disease 2019 (COVID-19). The first one is an 81-year-old man who received the BNT162b2 vaccine. He presented with bilateral hand weakness. Spine magnetic resonance imaging (MRI) showed high signal intensity from the C1 to C3 vertebrae. The second is a 23-year-old woman who received the BNT162b2 vaccine and experienced tingling in her legs. Spine MRI showed a high signal intensity lesion at the conus medullaris. These patients were treated with intravenous methylprednisolone and their symptoms improved slightly. Careful follow-up is needed to identify adverse events after the administration of mRNA vaccines for COVID-19.
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spelling pubmed-88607702022-03-03 Case Reports of Acute Transverse Myelitis Associated With mRNA Vaccine for COVID-19 Eom, Hyunjong Kim, Seung Woo Kim, Minkyoung Kim, Ye Eun Kim, Ji Hyun Shin, Ha Young Lee, Hye Lim J Korean Med Sci Case Report Acute transverse myelitis (ATM) has been reported as rare complication of vaccination. Herein, we report 2 cases of ATM after the administration of an mRNA vaccine for coronavirus disease 2019 (COVID-19). The first one is an 81-year-old man who received the BNT162b2 vaccine. He presented with bilateral hand weakness. Spine magnetic resonance imaging (MRI) showed high signal intensity from the C1 to C3 vertebrae. The second is a 23-year-old woman who received the BNT162b2 vaccine and experienced tingling in her legs. Spine MRI showed a high signal intensity lesion at the conus medullaris. These patients were treated with intravenous methylprednisolone and their symptoms improved slightly. Careful follow-up is needed to identify adverse events after the administration of mRNA vaccines for COVID-19. The Korean Academy of Medical Sciences 2022-02-08 /pmc/articles/PMC8860770/ /pubmed/35191229 http://dx.doi.org/10.3346/jkms.2022.37.e52 Text en © 2022 The Korean Academy of Medical Sciences. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Eom, Hyunjong
Kim, Seung Woo
Kim, Minkyoung
Kim, Ye Eun
Kim, Ji Hyun
Shin, Ha Young
Lee, Hye Lim
Case Reports of Acute Transverse Myelitis Associated With mRNA Vaccine for COVID-19
title Case Reports of Acute Transverse Myelitis Associated With mRNA Vaccine for COVID-19
title_full Case Reports of Acute Transverse Myelitis Associated With mRNA Vaccine for COVID-19
title_fullStr Case Reports of Acute Transverse Myelitis Associated With mRNA Vaccine for COVID-19
title_full_unstemmed Case Reports of Acute Transverse Myelitis Associated With mRNA Vaccine for COVID-19
title_short Case Reports of Acute Transverse Myelitis Associated With mRNA Vaccine for COVID-19
title_sort case reports of acute transverse myelitis associated with mrna vaccine for covid-19
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860770/
https://www.ncbi.nlm.nih.gov/pubmed/35191229
http://dx.doi.org/10.3346/jkms.2022.37.e52
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