Cell-Type Specific Deletion of CB2 Cannabinoid Receptors in Dopamine Neurons Induced Hyperactivity Phenotype: Possible Relevance to Attention-Deficit Hyperactivity Disorder

DAT-Cnr2 mice are conditional knockout (cKO) animals that do not express cannabinoid CB2 receptors (CB2R), in midbrain dopamine neurons. The hyperactivity phenotype of DAT-Cnr2 cKO mice were paradoxically reduced by low dose of amphetamine. Here, we report on the locomotor activity analysis in male...

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Detalles Bibliográficos
Autores principales: Canseco-Alba, Ana, Sanabria, Branden, Hammouda, Mariam, Bernadin, Rollanda, Mina, Marizel, Liu, Qing-Rong, Onaivi, Emmanuel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860836/
https://www.ncbi.nlm.nih.gov/pubmed/35211038
http://dx.doi.org/10.3389/fpsyt.2021.803394

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