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Use of computational toxicology tools to predict in vivo endpoints associated with Mode of Action and the endocannabinoid system: A case study with chlorpyrifos, chlorpyrifos-oxon and (Δ9)Tetrahydrocannabinol
Currently, there is a lack of knowledge about the effects of co-exposures of cannabis, contaminated with pesticides like chlorpyrifos (CPF) and the toxic metabolite CPF-oxon (CPFO). CPF/CPFO residues, and (Δ9)Tetrahydrocannabinol ((Δ9)THC), the main component in cannabis, are known to disrupt the en...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8860916/ https://www.ncbi.nlm.nih.gov/pubmed/35243363 http://dx.doi.org/10.1016/j.crtox.2022.100064 |