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Parental folate deficiency induces birth defects in mice accompanied with increased de novo mutations
Dietary folate deficiency (FD) is associated with the occurrence of birth defects. However, the mechanisms underlying this association remain elusive. In particular, how FD affects genome stability is unknown. To examine whether a folate-deficient diet can affect genome stability, C57BL/6 mice were...
Autores principales: | Zhao, Ying, Chen, Duoyuan, Tang, Jianping, Zheng, Yufang, Qi, Ji, Wang, Hongyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861018/ https://www.ncbi.nlm.nih.gov/pubmed/35190523 http://dx.doi.org/10.1038/s41421-021-00364-0 |
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