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Parental folate deficiency induces birth defects in mice accompanied with increased de novo mutations

Dietary folate deficiency (FD) is associated with the occurrence of birth defects. However, the mechanisms underlying this association remain elusive. In particular, how FD affects genome stability is unknown. To examine whether a folate-deficient diet can affect genome stability, C57BL/6 mice were...

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Detalles Bibliográficos
Autores principales: Zhao, Ying, Chen, Duoyuan, Tang, Jianping, Zheng, Yufang, Qi, Ji, Wang, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861018/
https://www.ncbi.nlm.nih.gov/pubmed/35190523
http://dx.doi.org/10.1038/s41421-021-00364-0

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