Redesigning therapies for pantothenate kinase–associated neurodegeneration

Pantothenate kinase–associated neurodegeneration (PKAN) is an incurable rare genetic disorder of children and young adults caused by mutations in the PANK2 gene, which encodes an enzyme critical for the biosynthesis of coenzyme A. Although PKAN affects only a small number of patients, it shares seve...

Descripción completa

Detalles Bibliográficos
Autores principales: Munshi, Muhammad I., Yao, Sarah J., Ben Mamoun, Choukri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
JBC Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861153/
https://www.ncbi.nlm.nih.gov/pubmed/35041826
http://dx.doi.org/10.1016/j.jbc.2022.101577

Ejemplares similares

Ejemplares similares