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Trimethylguanosine synthase 1 is a novel regulator of pancreatic beta-cell mass and function

Type 2 diabetes is a metabolic disorder associated with abnormal glucose homeostasis and is characterized by intrinsic defects in β-cell function and mass. Trimethylguanosine synthase 1 (TGS1) is an evolutionarily conserved enzyme that methylates small nuclear and nucleolar RNAs and that is involved...

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Detalles Bibliográficos
Autores principales:	Blandino-Rosano, Manuel, Romaguera Llacer, Pau, Lin, Ashley, Reddy, Janardan K., Bernal-Mizrachi, Ernesto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861161/ https://www.ncbi.nlm.nih.gov/pubmed/35041827 http://dx.doi.org/10.1016/j.jbc.2022.101592

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