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Measurement of deaminated cytosine adducts in DNA using a novel hybrid thymine DNA glycosylase

The hydrolytic deamination of cytosine and 5-methylcytosine drives many of the transition mutations observed in human cancer. The deamination-induced mutagenic intermediates include either uracil or thymine adducts mispaired with guanine. While a substantial array of methods exist to measure other t...

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Detalles Bibliográficos
Autores principales:	Hsu, Chia Wei, Sowers, Mark L., Baljinnyam, Tuvshintugs, Herring, Jason L., Hackfeld, Linda C., Tang, Hui, Zhang, Kangling, Sowers, Lawrence C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861164/ https://www.ncbi.nlm.nih.gov/pubmed/35085553 http://dx.doi.org/10.1016/j.jbc.2022.101638

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