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Ultrasounds induce blood–brain barrier opening across a sonolucent polyolefin plate in an in vitro isolated brain preparation

The blood–brain barrier (BBB) represents a major obstacle to the delivery of drugs to the central nervous system. The combined use of low-intensity pulsed ultrasound waves and intravascular microbubbles (MB) represents a promising solution to this issue, allowing reversible disruption of the barrier...

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Detalles Bibliográficos
Autores principales: Librizzi, Laura, Uva, Laura, Raspagliesi, Luca, Gionso, Matteo, Regondi, Maria Cristina, Durando, Giovanni, DiMeco, Francesco, de Curtis, Marco, Prada, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861168/
https://www.ncbi.nlm.nih.gov/pubmed/35190597
http://dx.doi.org/10.1038/s41598-022-06791-7