Dynamic disequilibrium-based pathogenicity model in mutated pyrin’s B30.2 domain—Casp1/p20 complex

BACKGROUND: The B30.2 variants lead to most relevant severity forms of familial Mediterranean fever (FMF) manifestations. The B30.2 domain plays a key role in protein-protein interaction (PPI) of pyrin with other apoptosis proteins and in regulation the cascade of inflammatory reactions. Pyrin-casp1...

Descripción completa

Detalles Bibliográficos
Autores principales: Fayez, Alaaeldin G., Eldeen, Ghada Nour, Zarouk, Waheba A., Hamed, Khaled, Ramadan, Abeer, Foda, Bardees M., Kobesiy, Maha M., Zekrie, Mai E., Lotfy, Randa S., Sokkar, Mona F., El-Bassyouni, Hala T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861233/
https://www.ncbi.nlm.nih.gov/pubmed/35190906
http://dx.doi.org/10.1186/s43141-022-00300-z

Ejemplares similares

Ejemplares similares