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The Effect of Hypoxia and Hypoxia-Associated Pathways in the Regulation of Antitumor Response: Friends or Foes?
Hypoxia is an environmental stressor that is instigated by low oxygen availability. It fuels the progression of solid tumors by driving tumor plasticity, heterogeneity, stemness and genomic instability. Hypoxia metabolically reprograms the tumor microenvironment (TME), adding insult to injury to the...
Autores principales: | Abou Khouzam, Raefa, Zaarour, Rania Faouzi, Brodaczewska, Klaudia, Azakir, Bilal, Venkatesh, Goutham Hassan, Thiery, Jerome, Terry, Stéphane, Chouaib, Salem |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861358/ https://www.ncbi.nlm.nih.gov/pubmed/35211123 http://dx.doi.org/10.3389/fimmu.2022.828875 |
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