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Combination of Venetoclax and Midostaurin Efficiently Suppressed Relapsed t(8;21)Acute Myeloid Leukemia With Mutant KIT After Failure of Venetoclax Plus Azacitidine Treatment

Acute myeloid leukemia (AML) with t(8;21) is categorized as favorable-risk AML, but KIT mutations show a significantly poor prognostic impact in such patients. Persistent vulnerability to relapse is a major challenge in the treatment of this subtype of patients. Venetoclax is a BCL-2 selective inhib...

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Detalles Bibliográficos
Autores principales:	Li, Zheng, Wang, Jun, Ge, Shuai-Shuai, Qiu, Qiao-Cheng, Du, Jia-Hui, Shan, Shuang-Shuang, Shen, Xiang-Dong, Wan, Chao-Ling, Wang, Bin-Ru, Wu, De-Pei, Qiu, Hui-Ying, Xue, Sheng-Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861361/ https://www.ncbi.nlm.nih.gov/pubmed/35211416 http://dx.doi.org/10.3389/fonc.2022.841276

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