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Clinical course of more than 10 years in a patient with extensive skin burns who received cultured epidermal autograft transplantation
Cultured epidermal autografts (CEAs) are used to treat extensive burns, giant congenital melanocytic nevi, and epidermolysis bullosa, but information about the long-term clinical course after CEA transplantation is scarce. Here we report 10 years’ progress of a 7-year-old Japanese girl who suffered...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Japanese Society for Regenerative Medicine
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861580/ https://www.ncbi.nlm.nih.gov/pubmed/35252486 http://dx.doi.org/10.1016/j.reth.2022.01.007 |
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author | Kan, Takanobu Takahagi, Shunsuke Matsubara, Daiki Murakami, Emi Kawai, Mikio Hide, Michihiro Tanaka, Akio |
author_facet | Kan, Takanobu Takahagi, Shunsuke Matsubara, Daiki Murakami, Emi Kawai, Mikio Hide, Michihiro Tanaka, Akio |
author_sort | Kan, Takanobu |
collection | PubMed |
description | Cultured epidermal autografts (CEAs) are used to treat extensive burns, giant congenital melanocytic nevi, and epidermolysis bullosa, but information about the long-term clinical course after CEA transplantation is scarce. Here we report 10 years’ progress of a 7-year-old Japanese girl who suffered from a scald burn injury affecting 80% of her total body surface area and was treated with CEA transplantation. The skin of a child with extensive burns treated with CEAs appeared soft and of a good texture, even after 10 years, and recovery of skin pigmentation and scar condition were better at sites with a combination of CEAs and autologous skin grafts than those with CEAs alone. |
format | Online Article Text |
id | pubmed-8861580 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Japanese Society for Regenerative Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-88615802022-03-04 Clinical course of more than 10 years in a patient with extensive skin burns who received cultured epidermal autograft transplantation Kan, Takanobu Takahagi, Shunsuke Matsubara, Daiki Murakami, Emi Kawai, Mikio Hide, Michihiro Tanaka, Akio Regen Ther Case Report Cultured epidermal autografts (CEAs) are used to treat extensive burns, giant congenital melanocytic nevi, and epidermolysis bullosa, but information about the long-term clinical course after CEA transplantation is scarce. Here we report 10 years’ progress of a 7-year-old Japanese girl who suffered from a scald burn injury affecting 80% of her total body surface area and was treated with CEA transplantation. The skin of a child with extensive burns treated with CEAs appeared soft and of a good texture, even after 10 years, and recovery of skin pigmentation and scar condition were better at sites with a combination of CEAs and autologous skin grafts than those with CEAs alone. Japanese Society for Regenerative Medicine 2022-02-17 /pmc/articles/PMC8861580/ /pubmed/35252486 http://dx.doi.org/10.1016/j.reth.2022.01.007 Text en © 2022 The Japanese Society for Regenerative Medicine. Production and hosting by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Kan, Takanobu Takahagi, Shunsuke Matsubara, Daiki Murakami, Emi Kawai, Mikio Hide, Michihiro Tanaka, Akio Clinical course of more than 10 years in a patient with extensive skin burns who received cultured epidermal autograft transplantation |
title | Clinical course of more than 10 years in a patient with extensive skin burns who received cultured epidermal autograft transplantation |
title_full | Clinical course of more than 10 years in a patient with extensive skin burns who received cultured epidermal autograft transplantation |
title_fullStr | Clinical course of more than 10 years in a patient with extensive skin burns who received cultured epidermal autograft transplantation |
title_full_unstemmed | Clinical course of more than 10 years in a patient with extensive skin burns who received cultured epidermal autograft transplantation |
title_short | Clinical course of more than 10 years in a patient with extensive skin burns who received cultured epidermal autograft transplantation |
title_sort | clinical course of more than 10 years in a patient with extensive skin burns who received cultured epidermal autograft transplantation |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861580/ https://www.ncbi.nlm.nih.gov/pubmed/35252486 http://dx.doi.org/10.1016/j.reth.2022.01.007 |
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