Cargando…

Clinical course of more than 10 years in a patient with extensive skin burns who received cultured epidermal autograft transplantation

Cultured epidermal autografts (CEAs) are used to treat extensive burns, giant congenital melanocytic nevi, and epidermolysis bullosa, but information about the long-term clinical course after CEA transplantation is scarce. Here we report 10 years’ progress of a 7-year-old Japanese girl who suffered...

Descripción completa

Detalles Bibliográficos
Autores principales: Kan, Takanobu, Takahagi, Shunsuke, Matsubara, Daiki, Murakami, Emi, Kawai, Mikio, Hide, Michihiro, Tanaka, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861580/
https://www.ncbi.nlm.nih.gov/pubmed/35252486
http://dx.doi.org/10.1016/j.reth.2022.01.007
_version_ 1784654914833612800
author Kan, Takanobu
Takahagi, Shunsuke
Matsubara, Daiki
Murakami, Emi
Kawai, Mikio
Hide, Michihiro
Tanaka, Akio
author_facet Kan, Takanobu
Takahagi, Shunsuke
Matsubara, Daiki
Murakami, Emi
Kawai, Mikio
Hide, Michihiro
Tanaka, Akio
author_sort Kan, Takanobu
collection PubMed
description Cultured epidermal autografts (CEAs) are used to treat extensive burns, giant congenital melanocytic nevi, and epidermolysis bullosa, but information about the long-term clinical course after CEA transplantation is scarce. Here we report 10 years’ progress of a 7-year-old Japanese girl who suffered from a scald burn injury affecting 80% of her total body surface area and was treated with CEA transplantation. The skin of a child with extensive burns treated with CEAs appeared soft and of a good texture, even after 10 years, and recovery of skin pigmentation and scar condition were better at sites with a combination of CEAs and autologous skin grafts than those with CEAs alone.
format Online
Article
Text
id pubmed-8861580
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Japanese Society for Regenerative Medicine
record_format MEDLINE/PubMed
spelling pubmed-88615802022-03-04 Clinical course of more than 10 years in a patient with extensive skin burns who received cultured epidermal autograft transplantation Kan, Takanobu Takahagi, Shunsuke Matsubara, Daiki Murakami, Emi Kawai, Mikio Hide, Michihiro Tanaka, Akio Regen Ther Case Report Cultured epidermal autografts (CEAs) are used to treat extensive burns, giant congenital melanocytic nevi, and epidermolysis bullosa, but information about the long-term clinical course after CEA transplantation is scarce. Here we report 10 years’ progress of a 7-year-old Japanese girl who suffered from a scald burn injury affecting 80% of her total body surface area and was treated with CEA transplantation. The skin of a child with extensive burns treated with CEAs appeared soft and of a good texture, even after 10 years, and recovery of skin pigmentation and scar condition were better at sites with a combination of CEAs and autologous skin grafts than those with CEAs alone. Japanese Society for Regenerative Medicine 2022-02-17 /pmc/articles/PMC8861580/ /pubmed/35252486 http://dx.doi.org/10.1016/j.reth.2022.01.007 Text en © 2022 The Japanese Society for Regenerative Medicine. Production and hosting by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kan, Takanobu
Takahagi, Shunsuke
Matsubara, Daiki
Murakami, Emi
Kawai, Mikio
Hide, Michihiro
Tanaka, Akio
Clinical course of more than 10 years in a patient with extensive skin burns who received cultured epidermal autograft transplantation
title Clinical course of more than 10 years in a patient with extensive skin burns who received cultured epidermal autograft transplantation
title_full Clinical course of more than 10 years in a patient with extensive skin burns who received cultured epidermal autograft transplantation
title_fullStr Clinical course of more than 10 years in a patient with extensive skin burns who received cultured epidermal autograft transplantation
title_full_unstemmed Clinical course of more than 10 years in a patient with extensive skin burns who received cultured epidermal autograft transplantation
title_short Clinical course of more than 10 years in a patient with extensive skin burns who received cultured epidermal autograft transplantation
title_sort clinical course of more than 10 years in a patient with extensive skin burns who received cultured epidermal autograft transplantation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861580/
https://www.ncbi.nlm.nih.gov/pubmed/35252486
http://dx.doi.org/10.1016/j.reth.2022.01.007
work_keys_str_mv AT kantakanobu clinicalcourseofmorethan10yearsinapatientwithextensiveskinburnswhoreceivedculturedepidermalautografttransplantation
AT takahagishunsuke clinicalcourseofmorethan10yearsinapatientwithextensiveskinburnswhoreceivedculturedepidermalautografttransplantation
AT matsubaradaiki clinicalcourseofmorethan10yearsinapatientwithextensiveskinburnswhoreceivedculturedepidermalautografttransplantation
AT murakamiemi clinicalcourseofmorethan10yearsinapatientwithextensiveskinburnswhoreceivedculturedepidermalautografttransplantation
AT kawaimikio clinicalcourseofmorethan10yearsinapatientwithextensiveskinburnswhoreceivedculturedepidermalautografttransplantation
AT hidemichihiro clinicalcourseofmorethan10yearsinapatientwithextensiveskinburnswhoreceivedculturedepidermalautografttransplantation
AT tanakaakio clinicalcourseofmorethan10yearsinapatientwithextensiveskinburnswhoreceivedculturedepidermalautografttransplantation