Starving lethal prostate cancer by targeting heat shock proteins and glycolytic enzymes

Metastatic prostate cancer remains uncurable. In this issue of Cell Reports Medicine, Rice et al. present an assessment of a compound (SU086) demonstrating activity in prostate cancer models through heat shock protein 90 inhibition and cell metabolism changes.

Detalles Bibliográficos
Autores principales: Plymate, Stephen R., Sprenger, Cynthia, Haffner, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Preview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861633/
https://www.ncbi.nlm.nih.gov/pubmed/35243412
http://dx.doi.org/10.1016/j.xcrm.2021.100493
Descripción
Sumario:Metastatic prostate cancer remains uncurable. In this issue of Cell Reports Medicine, Rice et al. present an assessment of a compound (SU086) demonstrating activity in prostate cancer models through heat shock protein 90 inhibition and cell metabolism changes.

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