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Characteristics and clinical outcomes of COVID‐19 patients with pulmonary disorders: A single‐center, retrospective observational study

INTRODUCTION: Mortality rates and clinical characteristics of patients with coronavirus disease 2019 (COVID‐19) admitted to the intensive care unit (ICU) vary significantly. OBJECTIVES: To describe the data of patients with pulmonary comorbidities who were admitted to the ICU with COVID‐19 in Qatar...

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Autores principales: Jamal, Wasim, Khatib, Mohamad Y., Al Wraidat, Mohammad, Ahmed, Amna, Ananthegowda, Dore C., Mohamed, Ahmed S., Aroos, Asra, Chandra, Prem, Hameed, Mansoor, Yousaf, Muhammad, Al‐Mohammed, Ahmed, Nashwan, Abdulqadir J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861842/
https://www.ncbi.nlm.nih.gov/pubmed/35229054
http://dx.doi.org/10.1002/hsr2.525
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author Jamal, Wasim
Khatib, Mohamad Y.
Al Wraidat, Mohammad
Ahmed, Amna
Ananthegowda, Dore C.
Mohamed, Ahmed S.
Aroos, Asra
Chandra, Prem
Hameed, Mansoor
Yousaf, Muhammad
Al‐Mohammed, Ahmed
Nashwan, Abdulqadir J.
author_facet Jamal, Wasim
Khatib, Mohamad Y.
Al Wraidat, Mohammad
Ahmed, Amna
Ananthegowda, Dore C.
Mohamed, Ahmed S.
Aroos, Asra
Chandra, Prem
Hameed, Mansoor
Yousaf, Muhammad
Al‐Mohammed, Ahmed
Nashwan, Abdulqadir J.
author_sort Jamal, Wasim
collection PubMed
description INTRODUCTION: Mortality rates and clinical characteristics of patients with coronavirus disease 2019 (COVID‐19) admitted to the intensive care unit (ICU) vary significantly. OBJECTIVES: To describe the data of patients with pulmonary comorbidities who were admitted to the ICU with COVID‐19 in Qatar in terms of demographic characteristics, coexisting conditions, imaging findings, and outcomes. METHODS: We conducted a retrospective study of the outcomes with regard to mortality and requirement of invasive ventilation, demographic characteristics, coexisting conditions, secondary infections, and imaging findings for critical care patients with COVID‐19 in Qatar who had pulmonary comorbidities between March and June 2020. RESULTS: A total of 923 patients were included, 29 (3.14%) were found to have pulmonary disease. All these 29 patients' respiratory disease was noted to be asthma. Among these, three patients (10.3%) died in the ICU within 28 days of ICU admission. They were all above 50 years old. Nineteen (66%) patients required intubation and mechanical ventilation. Twenty‐one (72.4%) patients were males. The most common comorbidities included diabetes mellitus (55.1%) and hypertension (62%). Eighteen (62%) patients developed secondary infections in the ICU. Five (17.24%) patients developed renal impairment. Twenty (69%) patients received tocilizumab as part of their COVID‐19 management, and out of these 16 (80%) patients developed a coinfection. CONCLUSION: Patients with pulmonary disorders had higher mortality rates than other patients admitted to ICU during the same time frame with similar comorbidities; these patients require extra consideration and care to avoid disease progression and death.
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spelling pubmed-88618422022-02-27 Characteristics and clinical outcomes of COVID‐19 patients with pulmonary disorders: A single‐center, retrospective observational study Jamal, Wasim Khatib, Mohamad Y. Al Wraidat, Mohammad Ahmed, Amna Ananthegowda, Dore C. Mohamed, Ahmed S. Aroos, Asra Chandra, Prem Hameed, Mansoor Yousaf, Muhammad Al‐Mohammed, Ahmed Nashwan, Abdulqadir J. Health Sci Rep Original Research INTRODUCTION: Mortality rates and clinical characteristics of patients with coronavirus disease 2019 (COVID‐19) admitted to the intensive care unit (ICU) vary significantly. OBJECTIVES: To describe the data of patients with pulmonary comorbidities who were admitted to the ICU with COVID‐19 in Qatar in terms of demographic characteristics, coexisting conditions, imaging findings, and outcomes. METHODS: We conducted a retrospective study of the outcomes with regard to mortality and requirement of invasive ventilation, demographic characteristics, coexisting conditions, secondary infections, and imaging findings for critical care patients with COVID‐19 in Qatar who had pulmonary comorbidities between March and June 2020. RESULTS: A total of 923 patients were included, 29 (3.14%) were found to have pulmonary disease. All these 29 patients' respiratory disease was noted to be asthma. Among these, three patients (10.3%) died in the ICU within 28 days of ICU admission. They were all above 50 years old. Nineteen (66%) patients required intubation and mechanical ventilation. Twenty‐one (72.4%) patients were males. The most common comorbidities included diabetes mellitus (55.1%) and hypertension (62%). Eighteen (62%) patients developed secondary infections in the ICU. Five (17.24%) patients developed renal impairment. Twenty (69%) patients received tocilizumab as part of their COVID‐19 management, and out of these 16 (80%) patients developed a coinfection. CONCLUSION: Patients with pulmonary disorders had higher mortality rates than other patients admitted to ICU during the same time frame with similar comorbidities; these patients require extra consideration and care to avoid disease progression and death. John Wiley and Sons Inc. 2022-02-22 /pmc/articles/PMC8861842/ /pubmed/35229054 http://dx.doi.org/10.1002/hsr2.525 Text en © 2022 The Authors. Health Science Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Jamal, Wasim
Khatib, Mohamad Y.
Al Wraidat, Mohammad
Ahmed, Amna
Ananthegowda, Dore C.
Mohamed, Ahmed S.
Aroos, Asra
Chandra, Prem
Hameed, Mansoor
Yousaf, Muhammad
Al‐Mohammed, Ahmed
Nashwan, Abdulqadir J.
Characteristics and clinical outcomes of COVID‐19 patients with pulmonary disorders: A single‐center, retrospective observational study
title Characteristics and clinical outcomes of COVID‐19 patients with pulmonary disorders: A single‐center, retrospective observational study
title_full Characteristics and clinical outcomes of COVID‐19 patients with pulmonary disorders: A single‐center, retrospective observational study
title_fullStr Characteristics and clinical outcomes of COVID‐19 patients with pulmonary disorders: A single‐center, retrospective observational study
title_full_unstemmed Characteristics and clinical outcomes of COVID‐19 patients with pulmonary disorders: A single‐center, retrospective observational study
title_short Characteristics and clinical outcomes of COVID‐19 patients with pulmonary disorders: A single‐center, retrospective observational study
title_sort characteristics and clinical outcomes of covid‐19 patients with pulmonary disorders: a single‐center, retrospective observational study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861842/
https://www.ncbi.nlm.nih.gov/pubmed/35229054
http://dx.doi.org/10.1002/hsr2.525
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