ABCC1 modulates negative feedback control of the hypothalamic-pituitary-adrenal axis in vivo in humans

BACKGROUND: Cortisol and corticosterone both circulate in human plasma and, due to differing export by ATP-binding cassette (ABC) transporters, may exert differential cellular effects. ABCB1 (expressed in brain) exports cortisol not corticosterone while ABCC1 (expressed in adipose and skeletal muscl...

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Detalles Bibliográficos
Autores principales: Kyle, Catriona J., Nixon, Mark, Homer, Natalie Z.M., Morgan, Ruth A., Andrew, Ruth, Stimson, Roland H., Walker, Brian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861854/
https://www.ncbi.nlm.nih.gov/pubmed/34990712
http://dx.doi.org/10.1016/j.metabol.2021.155118

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