Longitudinal Imaging of the Skull Base Synchondroses Demonstrate Prevention of a Premature Ossification After Recifercept Treatment in Mouse Model of Achondroplasia

Achondroplasia is the most common form of short‐limb dwarfism. In this disorder, endochondral ossification is impaired due to gain‐of‐function mutation in the Fibroblast Growth Factor Receptor 3 (FGFR3) gene. In addition to short limbs, cranial base bones are also affected leading to shortening of t...

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Detalles Bibliográficos
Autores principales: Rignol, Guylene, Garcia, Stephanie, Authier, Florence, Smith, Kaamula, Tosello, Lionel, Marsault, Raphael, Dellugat, Pierre, Goncalves, Diogo, Brouillard, Marlene, Stavenhagen, Jeffrey, Santarelli, Luca, Czech, Christian, Gouze, Elvire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861980/
https://www.ncbi.nlm.nih.gov/pubmed/35229060
http://dx.doi.org/10.1002/jbm4.10568

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