Activation of the GPR35 pathway drives angiogenesis in the tumour microenvironment

OBJECTIVE: Primary sclerosing cholangitis (PSC) is in 70% of cases associated with inflammatory bowel disease. The hypermorphic T108M variant of the orphan G protein-coupled receptor GPR35 increases risk for PSC and ulcerative colitis (UC), conditions strongly predisposing for inflammation-associate...

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Detalles Bibliográficos
Autores principales: Pagano, Ester, Elias, Joshua E, Schneditz, Georg, Saveljeva, Svetlana, Holland, Lorraine M, Borrelli, Francesca, Karlsen, Tom H, Kaser, Arthur, Kaneider, Nicole C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
GI cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862021/
https://www.ncbi.nlm.nih.gov/pubmed/33758004
http://dx.doi.org/10.1136/gutjnl-2020-323363

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