Introduction and expression of PIK3CA(E545K) in a papillary thyroid cancer BRAF(V600E) cell line leads to a dedifferentiated aggressive phenotype

Anaplastic thyroid cancer (ATC) is a rare, aggressive form of undifferentiated thyroid cancer, which exhibits rapid progression and is almost universally fatal. At least a subset of ATC is thought to arise from pre-existing well-differentiated thyroid cancer, most frequently papillary thyroid cancer...

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Detalles Bibliográficos
Autores principales: Pinto, Nicole, Ruicci, Kara M., Khan, Mohammed Imran, Shaikh, Mushfiq Hassan, Zeng, Yu Fan Peter, Yoo, John, Fung, Kevin, MacNeil, S. Danielle, Mendez, Adrian, Mymryk, Joe S., Barrett, John W., Boutros, Paul C., Nichols, Anthony C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862267/
https://www.ncbi.nlm.nih.gov/pubmed/35193694
http://dx.doi.org/10.1186/s40463-022-00558-w

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