Cargando…

A Comprehensive Prognostic Analysis of POLD1 in Hepatocellular Carcinoma

BACKGROUND: DNA polymerase delta 1 catalytic subunit (POLD1) plays a key role in DNA replication and damage repair. A defective DNA proofreading function caused by POLD1 mutation contributes to carcinogenesis, while POLD1 overexpression predicts poor prognosis in cancers. However, the effect of POLD...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Hui, You, Tingting, Sun, Zhao, Bai, Chunmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862270/ https://www.ncbi.nlm.nih.gov/pubmed/35189839 http://dx.doi.org/10.1186/s12885-022-09284-y

Ejemplares similares

Roles of human POLD1 and POLD3 in genome stability
por: Tumini, Emanuela, et al.
Publicado: (2016)

Extracellular Matrix-Based Gene Expression Signature Defines Two Prognostic Subtypes of Hepatocellular Carcinoma With Different Immune Microenvironment Characteristics
por: Tang, Hui, et al.
Publicado: (2022)

Investigation of Functional Synergism of CENPF and FOXM1 Identifies POLD1 as Downstream Target in Hepatocellular Carcinoma
por: Ho, Daniel Wai-Hung, et al.
Publicado: (2022)

POLE/POLD1 mutation and tumor immunotherapy
por: Ma, Xiaoting, et al.
Publicado: (2022)

Role of POLE and POLD1 in familial cancer
por: Mur, Pilar, et al.
Publicado: (2020)

POLD1 as a Prognostic Biomarker Correlated with Cell Proliferation and Immune Infiltration in Clear Cell Renal Cell Carcinoma
por: Tian, Junjie, et al.
Publicado: (2023)

Prospects of POLD1 in Human Cancers: A Review
por: Gola, Michał, et al.
Publicado: (2023)

CTCF Mediates Replicative Senescence Through POLD1
por: Hou, Yuli, et al.
Publicado: (2021)

An integrative analysis revealing POLD2 as a tumor suppressive immune protein and prognostic biomarker in pan-cancer
por: Cong, Fengyun, et al.
Publicado: (2022)

PARP1 and POLD2 as prognostic biomarkers for multiple myeloma in autologous stem cell transplant
por: Thomas, Melissa, et al.
Publicado: (2023)

Comprehensive analysis of POLE and POLD1 Gene Variations identifies cancer patients potentially benefit from immunotherapy in Chinese population
por: Yao, Jianfei, et al.
Publicado: (2019)

Recommendations for the classification of germline variants in the exonuclease domain of POLE and POLD1
por: Mur, Pilar, et al.
Publicado: (2023)

Scrutinizing Deleterious Nonsynonymous SNPs and Their Effect on Human POLD1 Gene
por: Bappy, Md. Nazmul Islam, et al.
Publicado: (2022)

Prognostic implications of alcohol dehydrogenases in hepatocellular carcinoma
por: Liu, Xiangye, et al.
Publicado: (2020)

Comprehensive analysis of the prognostic value and functions of prefoldins in hepatocellular carcinoma
por: Ke, Shanjia, et al.
Publicado: (2022)

Germline POLE and POLD1 proofreading domain mutations in endometrial carcinoma from Middle Eastern region
por: Siraj, Abdul K., et al.
Publicado: (2019)

Germline mutations in the proof-reading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas
por: Palles, Claire, et al.
Publicado: (2012)

Assessment of POLE and POLD1 mutations as prognosis and immunotherapy biomarkers for stomach adenocarcinoma
por: Zhu, Mingyu, et al.
Publicado: (2022)

Comprehensive Analysis of the Prognostic Values of the TRIM Family in Hepatocellular Carcinoma
por: Dai, Weiyu, et al.
Publicado: (2021)

POLE and POLD1 pathogenic variants in the proofreading domain in papillary thyroid cancer
por: Siraj, Abdul K, et al.
Publicado: (2020)

Human POLD1 modulates cell cycle progression and DNA damage repair
por: Song, Jing, et al.
Publicado: (2015)

Elevated expression of POLD1 is associated with poor prognosis in breast cancer
por: Qin, Qinghong, et al.
Publicado: (2018)

Comprehensive analysis of prognostic value and immune infiltration of IAPs family in hepatocellular carcinoma
por: Yang, Xuejie, et al.
Publicado: (2023)

E2F1 mediates the downregulation of POLD1 in replicative senescence
por: Gao, Shichao, et al.
Publicado: (2019)

Comprehensive analysis of prognostic value and immunotherapy prospect of brain cytoplasmic RNA1 in hepatocellular carcinoma
por: Han, Xiao-Yong, et al.
Publicado: (2023)

Construction and comprehensive analysis of a ceRNA network to reveal potential prognostic biomarkers for hepatocellular carcinoma
por: Long, Junyu, et al.
Publicado: (2019)

Comprehensive analysis of ASB3 as a prognostic biomarker in hepatocellular carcinoma
por: Qin, Zhongqiang, et al.
Publicado: (2023)

Risk of colorectal cancer for carriers of a germline mutation in POLE or POLD1
por: Buchanan, Daniel D., et al.
Publicado: (2017)

Preliminary study on the function of the POLD1 (CDC2) EXON2 c.56G>A mutation
por: Liu, Jing, et al.
Publicado: (2020)

POLD2 and KSP37 (FGFBP2) Correlate Strongly with Histology, Stage and Outcome in Ovarian Carcinomas
por: Elgaaen, Bente Vilming, et al.
Publicado: (2010)

CAD/POLD2 gene expression is associated with poor overall survival and chemoresistance in bladder urothelial carcinoma
por: Givechian, Kevin B., et al.
Publicado: (2018)

Detection of Allelic Variants of The POLE and POLD1 Genes in Colorectal Cancer Patients
por: Pätzold, LA, et al.
Publicado: (2017)

POLE/POLD1 mutation in non‐exonuclease domain matters for predicting efficacy of immune‐checkpoint‐inhibitor therapy
por: Chen, Yan‐Xing, et al.
Publicado: (2021)

Comprehensive analysis identifies CLEC1B as a potential prognostic biomarker in hepatocellular carcinoma
por: Jing, Qiangan, et al.
Publicado: (2023)

Comprehensive Analysis of HOX Family Members as Novel Diagnostic and Prognostic Markers for Hepatocellular Carcinoma
por: Jin, Zhipeng, et al.
Publicado: (2022)

Prognostic value of Notch-1 expression in hepatocellular carcinoma: a meta-analysis
por: Wu, Tao, et al.
Publicado: (2015)

Comprehensive Analysis of LPCATs Highlights the Prognostic and Immunological Values of LPCAT1/4 in Hepatocellular Carcinoma
por: Lin, Tong, et al.
Publicado: (2021)

Comprehensive Analysis of Prognostic Value and Immune Infiltration of the NT5DC Family in Hepatocellular Carcinoma
por: Li, Rongqi, et al.
Publicado: (2022)

POLE and POLD1 screening in 155 patients with multiple polyps and early-onset colorectal cancer
por: Esteban-Jurado, Clara, et al.
Publicado: (2017)

Comprehensive bioinformatic analysis of MMP1 in hepatocellular carcinoma and establishment of relevant prognostic model
por: Dai, Lei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ldklaqmv5p3or1u0eqqv6c7uuf