Overexpressed integrin alpha 2 inhibits the activation of the transforming growth factor β pathway in pancreatic cancer via the TFCP2-SMAD2 axis

BACKGROUND: Integrin alpha 2 (ITGA2) has been recently reported to be an oncogene and to play crucial roles in tumor cell proliferation, invasion, metastasis, and angiogenesis. Our previous study showed that ITGA2 was overexpressed in pancreatic cancer and promoted its progression. However, the mech...

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Detalles Bibliográficos
Autores principales: Cai, Hongkun, Guo, Feng, Wen, Shuang, Jin, Xin, Wu, Heshui, Ren, Dianyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862343/
https://www.ncbi.nlm.nih.gov/pubmed/35193647
http://dx.doi.org/10.1186/s13046-022-02286-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862343/
https://www.ncbi.nlm.nih.gov/pubmed/35193647
http://dx.doi.org/10.1186/s13046-022-02286-5

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