Epidural stimulation with locomotor training ameliorates unstable blood pressure after tetraplegia. A case report

A male with C7 complete tetraplegia participated in 14 weeks of body weight supported treadmill training (BWSTT) combined with spinal cord epidural stimulation (SCES), 4 weeks of no intervention, and two more weeks of BWSTT + SCES. The participant presented with unstable resting seated blood pressur...

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Autores principales: Gorgey, Ashraf S., Sutor, Tommy W., Goldsmith, Jacob A., Ennasr, Areej N., Lavis, Timothy D., Cifu, David X., Trainer, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Case Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862417/
https://www.ncbi.nlm.nih.gov/pubmed/35068086
http://dx.doi.org/10.1002/acn3.51508
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author Gorgey, Ashraf S.
Sutor, Tommy W.
Goldsmith, Jacob A.
Ennasr, Areej N.
Lavis, Timothy D.
Cifu, David X.
Trainer, Robert
author_facet Gorgey, Ashraf S.
Sutor, Tommy W.
Goldsmith, Jacob A.
Ennasr, Areej N.
Lavis, Timothy D.
Cifu, David X.
Trainer, Robert
author_sort Gorgey, Ashraf S.
collection PubMed
description A male with C7 complete tetraplegia participated in 14 weeks of body weight supported treadmill training (BWSTT) combined with spinal cord epidural stimulation (SCES), 4 weeks of no intervention, and two more weeks of BWSTT + SCES. The participant presented with unstable resting seated blood pressure (BP; 131/66 mmHg). After retrospective analysis, resting systolic BP decreased and diastolic BP increased, yielding a safe mean arterial BP. There was a fivefold increase in BWSTT bouts per session, and percentage of body weight support decreased to 69%. BWSTT + SCES safely and effectively regulated resting BP and mitigated symptoms of orthostatic intolerance. These effects were not maintained after 4 weeks without training.
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spelling pubmed-88624172022-02-27 Epidural stimulation with locomotor training ameliorates unstable blood pressure after tetraplegia. A case report Gorgey, Ashraf S. Sutor, Tommy W. Goldsmith, Jacob A. Ennasr, Areej N. Lavis, Timothy D. Cifu, David X. Trainer, Robert Ann Clin Transl Neurol Case Study A male with C7 complete tetraplegia participated in 14 weeks of body weight supported treadmill training (BWSTT) combined with spinal cord epidural stimulation (SCES), 4 weeks of no intervention, and two more weeks of BWSTT + SCES. The participant presented with unstable resting seated blood pressure (BP; 131/66 mmHg). After retrospective analysis, resting systolic BP decreased and diastolic BP increased, yielding a safe mean arterial BP. There was a fivefold increase in BWSTT bouts per session, and percentage of body weight support decreased to 69%. BWSTT + SCES safely and effectively regulated resting BP and mitigated symptoms of orthostatic intolerance. These effects were not maintained after 4 weeks without training. Blackwell Publishing Ltd 2022-01-23 /pmc/articles/PMC8862417/ /pubmed/35068086 http://dx.doi.org/10.1002/acn3.51508 Text en © 2022 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals LLC on behalf of American Neurological Association. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Study
Gorgey, Ashraf S.
Sutor, Tommy W.
Goldsmith, Jacob A.
Ennasr, Areej N.
Lavis, Timothy D.
Cifu, David X.
Trainer, Robert
Epidural stimulation with locomotor training ameliorates unstable blood pressure after tetraplegia. A case report
title Epidural stimulation with locomotor training ameliorates unstable blood pressure after tetraplegia. A case report
title_full Epidural stimulation with locomotor training ameliorates unstable blood pressure after tetraplegia. A case report
title_fullStr Epidural stimulation with locomotor training ameliorates unstable blood pressure after tetraplegia. A case report
title_full_unstemmed Epidural stimulation with locomotor training ameliorates unstable blood pressure after tetraplegia. A case report
title_short Epidural stimulation with locomotor training ameliorates unstable blood pressure after tetraplegia. A case report
title_sort epidural stimulation with locomotor training ameliorates unstable blood pressure after tetraplegia. a case report
topic Case Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862417/
https://www.ncbi.nlm.nih.gov/pubmed/35068086
http://dx.doi.org/10.1002/acn3.51508
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