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TLC599 in patients with osteoarthritis of the knee: a phase IIa, randomized, placebo-controlled, dose-finding study

BACKGROUND: Corticosteroid injection for knee osteoarthritis is limited by its modest duration of treatment effect. The liposome formulation of dexamethasone sodium phosphate (TLC599) was developed for the sustained relief of osteoarthritis pain. This clinical study was conducted to evaluate the eff...

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Detalles Bibliográficos
Autores principales: Hunter, David J., Chang, Chi-Ching, Wei, James Cheng-Chung, Lin, Hsiao-Yi, Brown, Carl, Tai, Tien-Tzu, Wu, Chih-Feng, Chuang, Wing Chia-Ming, Shih, Sheue-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862584/
https://www.ncbi.nlm.nih.gov/pubmed/35189943
http://dx.doi.org/10.1186/s13075-022-02739-4

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