A model of persistent post SARS-CoV-2 induced lung disease for target identification and testing of therapeutic strategies

COVID-19 survivors develop post-acute sequelae of SARS-CoV-2 (PASC), but the mechanistic basis of PASC-associated lung abnormalities suffers from a lack of longitudinal samples. Mouse-adapted SARS-CoV-2 MA10 produces an acute respiratory distress syndrome (ARDS) in mice similar to humans. To investi...

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Detalles Bibliográficos
Autores principales: Dinnon, Kenneth H., Leist, Sarah R., Okuda, Kenichi, Dang, Hong, Fritch, Ethan J., Gully, Kendra L., De la Cruz, Gabriela, Evangelista, Mia D., Asakura, Takanori, Gilmore, Rodney C., Hawkins, Padraig, Nakano, Satoko, West, Ande, Schäfer, Alexandra, Gralinski, Lisa E., Everman, Jamie L., Sajuthi, Satria P., Zweigart, Mark R., Dong, Stephanie, McBride, Jennifer, Cooley, Michelle R., Hines, Jesse B., Love, Miriya K., Groshong, Steve D., VanSchoiack, Alison, Phelan, Stefan J., Liang, Yan, Hether, Tyler, Leon, Michael, Zumwalt, Ross E., Barton, Lisa M., Duval, Eric J., Mukhopadhyay, Sanjay, Stroberg, Edana, Borczuk, Alain, Thorne, Leigh B., Sakthivel, Muthu K., Lee, Yueh Z., Hagood, James S., Mock, Jason R., Seibold, Max A., O’Neal, Wanda K., Montgomery, Stephanie A., Boucher, Richard C., Baric, Ralph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863140/
https://www.ncbi.nlm.nih.gov/pubmed/35194605
http://dx.doi.org/10.1101/2022.02.15.480515

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