The mechanism of RNA capping by SARS-CoV-2

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The SARS-CoV-2 RNA genome contains a 5′-cap that facilitates translation of viral proteins, protection from exonucleases and evasion of the host immune response(1-4). How this cap is made is not completely understood. Here, we reconstitute the SARS-CoV-2 (7Me)GpppA(2′-O-Me)-RNA cap using virally enc...

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Detalles Bibliográficos
Autores principales: Park, Gina J., Osinski, Adam, Hernandez, Genaro, Eitson, Jennifer L., Majumdar, Abir, Tonelli, Marco, Henzler-Wildman, Katie, Pawłowski, Krzysztof, Chen, Zhe, Li, Yang, Schoggins, John W., Tagliabracci, Vincent S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863163/
https://www.ncbi.nlm.nih.gov/pubmed/35194601
http://dx.doi.org/10.21203/rs.3.rs-1336910/v1
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