Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness

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Repeated emergence of SARS-CoV-2 variants with increased fitness necessitates rapid detection and characterization of new lineages. To address this need, we developed PyR(0,) a hierarchical Bayesian multinomial logistic regression model that infers relative prevalence of all viral lineages across ge...

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Detalles Bibliográficos
Autores principales: Obermeyer, Fritz, Jankowiak, Martin, Barkas, Nikolaos, Schaffner, Stephen F., Pyle, Jesse D., Yurkovetskiy, Lonya, Bosso, Matteo, Park, Daniel J., Babadi, Mehrtash, MacInnis, Bronwyn L., Luban, Jeremy, Sabeti, Pardis C., Lemieux, Jacob E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863165/
https://www.ncbi.nlm.nih.gov/pubmed/35194619
http://dx.doi.org/10.1101/2021.09.07.21263228
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