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STopTox: An in Silico Alternative to Animal Testing for Acute Systemic and Topical Toxicity
BACKGROUND: Modern chemical toxicology is facing a growing need to Reduce, Refine, and Replace animal tests (Russell 1959) for hazard identification. The most common type of animal assays for acute toxicity assessment of chemicals used as pesticides, pharmaceuticals, or in cosmetic products is known...
Autores principales: | Borba, Joyce V.B., Alves, Vinicius M., Braga, Rodolpho C., Korn, Daniel R., Overdahl, Kirsten, Silva, Arthur C., Hall, Steven U.S., Overdahl, Erik, Kleinstreuer, Nicole, Strickland, Judy, Allen, David, Andrade, Carolina Horta, Muratov, Eugene N., Tropsha, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Environmental Health Perspectives
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863177/ https://www.ncbi.nlm.nih.gov/pubmed/35192406 http://dx.doi.org/10.1289/EHP9341 |
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