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STopTox: An in Silico Alternative to Animal Testing for Acute Systemic and Topical Toxicity

BACKGROUND: Modern chemical toxicology is facing a growing need to Reduce, Refine, and Replace animal tests (Russell 1959) for hazard identification. The most common type of animal assays for acute toxicity assessment of chemicals used as pesticides, pharmaceuticals, or in cosmetic products is known...

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Detalles Bibliográficos
Autores principales: Borba, Joyce V.B., Alves, Vinicius M., Braga, Rodolpho C., Korn, Daniel R., Overdahl, Kirsten, Silva, Arthur C., Hall, Steven U.S., Overdahl, Erik, Kleinstreuer, Nicole, Strickland, Judy, Allen, David, Andrade, Carolina Horta, Muratov, Eugene N., Tropsha, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863177/
https://www.ncbi.nlm.nih.gov/pubmed/35192406
http://dx.doi.org/10.1289/EHP9341

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