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Clinical and Molecular Correlates of Abnormal Changes in the Cerebellum and Globus Pallidus in Fragile X Premutation

BACKGROUND: Fragile X premutation carriers (55–200 CGG triplets) may develop a progressive neurodegenerative disorder, fragile X-associated tremor/ataxia syndrome (FXTAS), after the age of 50. The neuroradiologic markers of FXTAS are hyperintense T2-signals in the middle cerebellar peduncle—the MCP...

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Detalles Bibliográficos
Autores principales:	Wang, Jun Yi, Grigsby, Jim, Placido, Diego, Wei, Hongjiang, Tassone, Flora, Kim, Kyoungmi, Hessl, David, Rivera, Susan M., Hagerman, Randi J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863211/ https://www.ncbi.nlm.nih.gov/pubmed/35211082 http://dx.doi.org/10.3389/fneur.2022.797649

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