Interpreting coronary artery disease GWAS results: A functional genomics approach assessing biological significance

Genome-wide association studies (GWAS) have implicated 58 loci in coronary artery disease (CAD). However, the biological basis for these associations, the relevant genes, and causative variants often remain uncertain. Since the vast majority of GWAS loci reside outside coding regions, most exert reg...

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Detalles Bibliográficos
Autores principales: Hartmann, Katherine, Seweryn, Michał, Sadee, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863290/
https://www.ncbi.nlm.nih.gov/pubmed/35192625
http://dx.doi.org/10.1371/journal.pone.0244904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863290/
https://www.ncbi.nlm.nih.gov/pubmed/35192625
http://dx.doi.org/10.1371/journal.pone.0244904

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