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Interpreting coronary artery disease GWAS results: A functional genomics approach assessing biological significance
Genome-wide association studies (GWAS) have implicated 58 loci in coronary artery disease (CAD). However, the biological basis for these associations, the relevant genes, and causative variants often remain uncertain. Since the vast majority of GWAS loci reside outside coding regions, most exert reg...
Autores principales: | Hartmann, Katherine, Seweryn, Michał, Sadee, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863290/ https://www.ncbi.nlm.nih.gov/pubmed/35192625 http://dx.doi.org/10.1371/journal.pone.0244904 |
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