Cargando…

Investigating the Impact of Optimized Trans-Cinnamic Acid-Loaded PLGA Nanoparticles on Epithelial to Mesenchymal Transition in Breast Cancer

PURPOSE: To design and optimize trans-cinnamic acid-loaded PLGA nanoparticles (CIN-PLGA-NPs) and assess its inhibitory effect on epithelial-mesenchymal transition (EMT) in triple-negative breast cancer. METHODS: The quality by design approach was used to correlate the formulation parameters (PLGA am...

Descripción completa

Detalles Bibliográficos
Autores principales:	Badawi, Noha M, Attia, Yasmeen M, El-Kersh, Dina M, Hammam, Olfat A, Khalifa, Maha K A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863342/ https://www.ncbi.nlm.nih.gov/pubmed/35210772 http://dx.doi.org/10.2147/IJN.S345870

Ejemplares similares

Detection of Epithelial-Mesenchymal Transition Markers in High Grade Bladder Cancer and Special Variants of Urothelial Carcinoma
por: Khalil, Heba, et al.
Publicado: (2022)

Wharton’s jelly-derived mesenchymal stem cells combined with praziquantel as a potential therapy for Schistosoma mansoni-induced liver fibrosis
por: Hammam, Olfat A., et al.
Publicado: (2016)

Corrigendum: Wharton’s jelly-derived mesenchymal stem cells combined with praziquantel as a potential therapy for Schistosoma mansoni-induced liver fibrosis
por: Hammam, Olfat A., et al.
Publicado: (2016)

Telmisartan, an AT1 receptor blocker and a PPAR gamma activator, alleviates liver fibrosis induced experimentally by Schistosoma mansoni infection
por: Attia, Yasmeen M, et al.
Publicado: (2013)

Short-Term Effects of Trans-Cinnamic Acid on the Metabolism of Zea mays L. Roots
por: López-González, David, et al.
Publicado: (2023)

2,3,4,5,6-Pentafluoro-trans-cinnamic acid
por: Navarrete, Angélica, et al.
Publicado: (2013)

Trans-Cinnamic Acid Stimulates White Fat Browning and Activates Brown Adipocytes
por: Kang, Nam Hyeon, et al.
Publicado: (2019)

trans-Cinnamic acid-induced leaf expansion involves an auxin-independent component
por: Kurepa, Jasmina, et al.
Publicado: (2019)

Opposing effects of trans‐ and cis‐cinnamic acid during rice coleoptile elongation
por: Vlaminck, Lena, et al.
Publicado: (2022)

Verbascoside: Identification, Quantification, and Potential Sensitization of Colorectal Cancer Cells to 5-FU by Targeting PI3K/AKT Pathway
por: Attia, Yasmeen M., et al.
Publicado: (2018)

Author Correction: Verbascoside: Identification, Quantification, and Potential Sensitization of Colorectal Cancer Cells to 5-FU by Targeting PI3K/AKT Pathway
por: Attia, Yasmeen M., et al.
Publicado: (2019)

Tendon Biomimetic Electrospun PLGA Fleeces Induce an Early Epithelial-Mesenchymal Transition and Tenogenic Differentiation on Amniotic Epithelial Stem Cells
por: Russo, Valentina, et al.
Publicado: (2020)

Rational Engineering of Phenylalanine Accumulation in Pseudomonas taiwanensis to Enable High-Yield Production of Trans-Cinnamate
por: Otto, Maike, et al.
Publicado: (2019)

Creatininium cinnamate
por: Ali, A. Jahubar, et al.
Publicado: (2011)

Association of MALAT1 and PVT1 Variants, Expression Profiles and Target miRNA-101 and miRNA-186 with Colorectal Cancer: Correlation with Epithelial-Mesenchymal Transition
por: Radwan, Abdullah F., et al.
Publicado: (2021)

Anti-estrogenic and anti-aromatase activities of citrus peels major compounds in breast cancer
por: El-Kersh, Dina M., et al.
Publicado: (2021)

Clinical comparative study of optimized metronidazole loaded lipid nanocarrier vaginal emulgel for management of bacterial vaginosis and its recurrence
por: Badawi, Noha M., et al.
Publicado: (2021)

Colon-Targeted Trans-Cinnamic Acid Ameliorates Rat Colitis by Activating GPR109A
por: Kang, Changyu, et al.
Publicado: (2022)

Tetraaquabis(4,4′-bipyridine)zinc(II) bis(trans-4-hydroxycinnamate)
por: Chen, Ling
Publicado: (2009)

Microwave-Assisted Synthesis of trans-Cinnamic Acid for Highly Efficient Removal of Copper from Aqueous Solution
por: Dávila-Guzmán, Nancy E., et al.
Publicado: (2019)

Production of trans-cinnamic acid by whole-cell bioconversion from l-phenylalanine in engineered Corynebacterium glutamicum
por: Son, Jaewoo, et al.
Publicado: (2021)

Structure−Activity Relationship (SAR) Study of trans-Cinnamic Acid and Derivatives on the Parasitic Weed Cuscuta campestris
por: Moreno-Robles, Antonio, et al.
Publicado: (2023)

Reduced Cardiotoxicity of Ponatinib-Loaded PLGA-PEG-PLGA Nanoparticles in Zebrafish Xenograft Model
por: Al-Thani, Hissa F., et al.
Publicado: (2022)

Development of VEGF-loaded PLGA matrices in association with mesenchymal stem cells for tissue engineering
por: Rosa, A.R., et al.
Publicado: (2017)

Protein Loading into Spongelike PLGA Microspheres
por: Kim, Yuyoung, et al.
Publicado: (2021)

Prenylated Trans-Cinnamic Esters and Ethers against Clinical Fusarium spp.: Repositioning of Natural Compounds in Antimicrobial Discovery
por: Oufensou, Safa, et al.
Publicado: (2021)

Topical 5 fluorouracil cream vs combined 5 fluorouracil and fractional erbium YAG laser for treatment of severe hypertrophic scars
por: Tawfik, Abeer Attia, et al.
Publicado: (2019)

Cinnamate-based DNA photolithography
por: Feng, Lang, et al.
Publicado: (2013)

Multifunctional Cinnamic Acid Derivatives
por: Peperidou, Aikaterini, et al.
Publicado: (2017)

Impact of Cyclin D1 and Heterogeneous Nuclear Ribonucleoprotein-K (HnRNP-K) on Urinary Bladder Carcinogenesis
por: Aboushousha, Tarek, et al.
Publicado: (2018)

The prevalence of Gasterophilus intestinalis (Diptera: Oestridae) in donkeys (Equus asinus) in Egypt with special reference to larvicidal effects of neem seed oil extract (Azadirachta indica) on third stage larvae
por: Attia, Marwa M., et al.
Publicado: (2018)

Tackling acne vulgaris by fabrication of tazarotene-loaded essential oil-based microemulsion: In vitro and in vivo evaluation
por: Badawi, Noha M., et al.
Publicado: (2023)

Retinoic acid-loaded PLGA nanocarriers targeting cell cholesterol potentialize the antitumour effect of PD-L1 antibody by preventing epithelial-mesenchymal transition mediated by M2-TAM in colorectal cancer
por: Júnior, Raimundo Fernandes de Araújo, et al.
Publicado: (2023)

Docetaxel-loaded PLGA and PLGA-PEG nanoparticles for intravenous application: pharmacokinetics and biodistribution profile
por: Rafiei, Pedram, et al.
Publicado: (2017)

Metabolic Plasticity and Epithelial-Mesenchymal Transition
por: Thomson, Timothy M., et al.
Publicado: (2019)

Pomegranate extract-loaded solid lipid nanoparticles: design, optimization, and in vitro cytotoxicity study
por: Badawi, Noha M, et al.
Publicado: (2018)

Targeting lung cancer initiating cells by all-trans retinoic acid-loaded lipid-PLGA nanoparticles with CD133 aptamers
por: Zhang, Yu, et al.
Publicado: (2018)

Mesenchymal Cells Affect Salivary Epithelial Cell Morphology on PGS/PLGA Core/Shell Nanofibers
por: Sfakis, Lauren, et al.
Publicado: (2018)

Mechanisms for Improving Hepatic Glucolipid Metabolism by Cinnamic Acid and Cinnamic Aldehyde: An Insight Provided by Multi-Omics
por: Wu, You, et al.
Publicado: (2022)

Inhibition of histone deacetylases by trans-cinnamic acid and its antitumor effect against colon cancer xenografts in athymic mice
por: ZHU, BINGYAN, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_sbqqtq6u2hvndhjf588k9r8tbp