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Trichoblastic fibroma mimicking sarcoma

Trichoblastic fibroma (TF) is a benign trichogenic tumour that has both epithelial and mesenchymal components and exhibits partial to complete follicular induction.TF is rare and in our case it is mimicking sarcoma. We report a 35-year-old gentleman who presented with a lump over his left lower leg...

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Autores principales: Hotak, Mirwais Khan, He, Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863396/
https://www.ncbi.nlm.nih.gov/pubmed/35211288
http://dx.doi.org/10.1093/jscr/rjac042
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author Hotak, Mirwais Khan
He, Mike
author_facet Hotak, Mirwais Khan
He, Mike
author_sort Hotak, Mirwais Khan
collection PubMed
description Trichoblastic fibroma (TF) is a benign trichogenic tumour that has both epithelial and mesenchymal components and exhibits partial to complete follicular induction.TF is rare and in our case it is mimicking sarcoma. We report a 35-year-old gentleman who presented with a lump over his left lower leg for the last 15 years. The lump was gradually increasing in size with a slight discomfort, no pain or any other symptoms. Consequently, the patient had an ultrasound which revealed bilobed solid lesion, and ultrasound-guided core biopsy revealed basaloid neoplasm. After positron emission tomography scan and discussion in MDT wide local excision performed. The histopathology revealed TF. Hence, TF should be included in differential diagnosis of relative superficial suspicious sarcomas. If there is any suspicion and changes in behaviour of long-term stable nodules they should be excised with a clear margin as there are aggressive TF reported in the literature.
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spelling pubmed-88633962022-02-23 Trichoblastic fibroma mimicking sarcoma Hotak, Mirwais Khan He, Mike J Surg Case Rep Case Report Trichoblastic fibroma (TF) is a benign trichogenic tumour that has both epithelial and mesenchymal components and exhibits partial to complete follicular induction.TF is rare and in our case it is mimicking sarcoma. We report a 35-year-old gentleman who presented with a lump over his left lower leg for the last 15 years. The lump was gradually increasing in size with a slight discomfort, no pain or any other symptoms. Consequently, the patient had an ultrasound which revealed bilobed solid lesion, and ultrasound-guided core biopsy revealed basaloid neoplasm. After positron emission tomography scan and discussion in MDT wide local excision performed. The histopathology revealed TF. Hence, TF should be included in differential diagnosis of relative superficial suspicious sarcomas. If there is any suspicion and changes in behaviour of long-term stable nodules they should be excised with a clear margin as there are aggressive TF reported in the literature. Oxford University Press 2022-02-22 /pmc/articles/PMC8863396/ /pubmed/35211288 http://dx.doi.org/10.1093/jscr/rjac042 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2022. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Hotak, Mirwais Khan
He, Mike
Trichoblastic fibroma mimicking sarcoma
title Trichoblastic fibroma mimicking sarcoma
title_full Trichoblastic fibroma mimicking sarcoma
title_fullStr Trichoblastic fibroma mimicking sarcoma
title_full_unstemmed Trichoblastic fibroma mimicking sarcoma
title_short Trichoblastic fibroma mimicking sarcoma
title_sort trichoblastic fibroma mimicking sarcoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863396/
https://www.ncbi.nlm.nih.gov/pubmed/35211288
http://dx.doi.org/10.1093/jscr/rjac042
work_keys_str_mv AT hotakmirwaiskhan trichoblasticfibromamimickingsarcoma
AT hemike trichoblasticfibromamimickingsarcoma