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Trichoblastic fibroma mimicking sarcoma
Trichoblastic fibroma (TF) is a benign trichogenic tumour that has both epithelial and mesenchymal components and exhibits partial to complete follicular induction.TF is rare and in our case it is mimicking sarcoma. We report a 35-year-old gentleman who presented with a lump over his left lower leg...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863396/ https://www.ncbi.nlm.nih.gov/pubmed/35211288 http://dx.doi.org/10.1093/jscr/rjac042 |
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author | Hotak, Mirwais Khan He, Mike |
author_facet | Hotak, Mirwais Khan He, Mike |
author_sort | Hotak, Mirwais Khan |
collection | PubMed |
description | Trichoblastic fibroma (TF) is a benign trichogenic tumour that has both epithelial and mesenchymal components and exhibits partial to complete follicular induction.TF is rare and in our case it is mimicking sarcoma. We report a 35-year-old gentleman who presented with a lump over his left lower leg for the last 15 years. The lump was gradually increasing in size with a slight discomfort, no pain or any other symptoms. Consequently, the patient had an ultrasound which revealed bilobed solid lesion, and ultrasound-guided core biopsy revealed basaloid neoplasm. After positron emission tomography scan and discussion in MDT wide local excision performed. The histopathology revealed TF. Hence, TF should be included in differential diagnosis of relative superficial suspicious sarcomas. If there is any suspicion and changes in behaviour of long-term stable nodules they should be excised with a clear margin as there are aggressive TF reported in the literature. |
format | Online Article Text |
id | pubmed-8863396 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-88633962022-02-23 Trichoblastic fibroma mimicking sarcoma Hotak, Mirwais Khan He, Mike J Surg Case Rep Case Report Trichoblastic fibroma (TF) is a benign trichogenic tumour that has both epithelial and mesenchymal components and exhibits partial to complete follicular induction.TF is rare and in our case it is mimicking sarcoma. We report a 35-year-old gentleman who presented with a lump over his left lower leg for the last 15 years. The lump was gradually increasing in size with a slight discomfort, no pain or any other symptoms. Consequently, the patient had an ultrasound which revealed bilobed solid lesion, and ultrasound-guided core biopsy revealed basaloid neoplasm. After positron emission tomography scan and discussion in MDT wide local excision performed. The histopathology revealed TF. Hence, TF should be included in differential diagnosis of relative superficial suspicious sarcomas. If there is any suspicion and changes in behaviour of long-term stable nodules they should be excised with a clear margin as there are aggressive TF reported in the literature. Oxford University Press 2022-02-22 /pmc/articles/PMC8863396/ /pubmed/35211288 http://dx.doi.org/10.1093/jscr/rjac042 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2022. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Report Hotak, Mirwais Khan He, Mike Trichoblastic fibroma mimicking sarcoma |
title | Trichoblastic fibroma mimicking sarcoma |
title_full | Trichoblastic fibroma mimicking sarcoma |
title_fullStr | Trichoblastic fibroma mimicking sarcoma |
title_full_unstemmed | Trichoblastic fibroma mimicking sarcoma |
title_short | Trichoblastic fibroma mimicking sarcoma |
title_sort | trichoblastic fibroma mimicking sarcoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863396/ https://www.ncbi.nlm.nih.gov/pubmed/35211288 http://dx.doi.org/10.1093/jscr/rjac042 |
work_keys_str_mv | AT hotakmirwaiskhan trichoblasticfibromamimickingsarcoma AT hemike trichoblasticfibromamimickingsarcoma |