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Maximal Information Coefficient-Based Testing to Identify Epistasis in Case-Control Association Studies

Interactions between genetic variants (epistasis) are ubiquitous in the model system and can significantly affect evolutionary adaptation, genetic mapping, and precision medical efforts. In this paper, we proposed a method for epistasis detection, called EpiMIC (epistasis detection through a maximal...

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Detalles Bibliográficos
Autores principales: Guo, Yingjie, Yuan, Zhian, Liang, Zhen, Wang, Yang, Wang, Yanpeng, Xu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863443/
https://www.ncbi.nlm.nih.gov/pubmed/35211187
http://dx.doi.org/10.1155/2022/7843990

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