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Impact of Notch3 Activation on Aortic Aneurysm Development in Marfan Syndrome

BACKGROUND: The leading cause of mortality in patients with Marfan syndrome (MFS) is thoracic aortic aneurysm and dissection. Notch signaling is essential for vessel morphogenesis and function. However, the role of Notch signaling in aortic pathology and aortic smooth muscle cell (SMC) differentiati...

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Detalles Bibliográficos
Autores principales:	Jespersen, Kathryn, Li, Chenxin, Batra, Rishi, Stephenson, Christopher A., Harding, Paul, Sestak, Kylie, Foley, Ryan T., Greene, Harrison, Meisinger, Trevor, Cook, Jason R., Baxter, B. Timothy, Xiong, Wanfen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863478/ https://www.ncbi.nlm.nih.gov/pubmed/35211631 http://dx.doi.org/10.1155/2022/7538649

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