Pharmacological Inhibition of Glutaminase 1 Normalized the Metabolic State and CD4+ T Cell Response in Sjogren's Syndrome

Previous studies have shown that abnormal metabolic reprogramming in CD4+ T cells could explain the occurrence of several autoimmune disorders, including Sjogren's syndrome (SS). However, therapeutic targets of the abnormal metabolism of CD4+ T cells remain to be explored. Here, we report that...

Descripción completa

Detalles Bibliográficos
Autores principales: Fu, Jiayao, Pu, Yiping, Wang, Baoli, Li, Hui, Yang, Xiujuan, Xie, Lisong, Shi, Huan, Wang, Zhijun, Yin, Junhao, Zhan, Tianle, Shao, Yanxiong, Chen, Changyu, Luo, Qi, Xu, Jiabao, Zong, Zirui, Wei, Xindi, Xiao, Wanwen, Yu, Chuangqi, Zheng, Lingyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8863479/
https://www.ncbi.nlm.nih.gov/pubmed/35211629
http://dx.doi.org/10.1155/2022/3210200

Ejemplares similares

Ejemplares similares